Table 2 SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) schedule of enrollment, interventions, and assessments

 Eligibility screen

X

 Informed consent

X

 Randomization

X

Interventions

 Intervention 1

X

X

X

X

X

 Control

X

X

X

Assessments

 ASSIST

X

 Demographics

X

 MOUD utilization

X

X

 Employment

X

X

 Depression (PHQ-9)

X

X

 Anxiety (GAD-7)

X

X

 Social support (MSPSS)

X

 Overdoses

X

X

 Pain intensity and frequency (PEG)

X

X

 30-day opioid (and other substance) use (adapted from NSDUH)

X

X

 SUD treatment utilization (adapted from NSDUH)

X

X

 SUD healthcare and mental health utilization (adapted from GAIN)

X

X

 Opinions about MOUD

X

 Severity of substance use (PROMIS)

X

X

 Patient experience of stigma

X

 Significant other with OUD

X

 Criminal justice involvement

X

 Patient experience of chronic illness care (PACIC)

X

 Therapeutic alliance (CAHPS)^a

X

 Satisfaction with START^a

X