Table 2 Laboratory findings of all reported cases of levamisole-induced cutaneous vasculitis in patients with cocaine use
Authors | Age/Sex | Leucopenia and/or Neutropenia | Antibodies present |
|---|---|---|---|
Gross RL et al.[3] | 50 years/M | Yes, WBC -3,300/μL, ANC -2400/μL | p-ANCA, ANA, LAC, c-ANCA, anti-ds-DNA |
42 years/M | Yes, WBC -3,200/μL, ANC - 800/μL | p-ANCA, ANA, LAC, c-ANCA, IgM ACL | |
42 years/F | No | p-ANCA, c-ANCA, ANA | |
59 years/F | No | p-ANCA, ANA, anti-RNP | |
Ullrich K et al.[4] | 45 years/M | Yes, WBC -1,900/μL, ANC -1,000/μL | p-ANCA, c-ANCA, ANA, IgM ACL |
49 years/F | Yes, WBC -3,500/μL, ANC – 0 (zero) | ANA, c-ANCA | |
27 years/F | Yes, WBC -1,800/μL, ANC -400/μL | p-ANCA, c-ANCA, IgM ACL, ANA | |
29 years/F | No | p-ANCA, c-ANCA, IgM ACL, ANA | |
55 years/F | Yes, WBC -3,700/μL, ANC -2,300/μL | p-ANCA, c-ANCA, IgM ACL | |
Bradford M et al.[7] | 57 years/F | Yes, ANC -500/μL | p-ANCA, IgM ACL |
22 years/F | Yes, ANC < 1,000/μL | p-ANCA, IgM ACL | |
Buchanan JA et al.[8] | Not specified/M | Yes, WBC -1,900/μL | Not reported |
Walsh NMG et al.[9] | 39 years/F | No | p-ANCA, c-ANCA, ANA, LAC, anti-HNE |
49 years/F | Yes, WBC -2,000/μL, ANC -400/μL | p-ANCA, c-ANCA, ANA, anti-HNE | |
Waller JM et al.[10] | 38 years/F | Yes, ANC -550/μL | p-ANCA, c-ANCA, LAC |
43 years/F | Yes, ANC -560/μL | p-ANCA, IgM ACL, LAC, anti-ds-DNA, | |
Farhat EK et al.[11] | 43 years/F | No | p-ANCA |
41 years/F | No | p-ANCA, IgM ACL | |
Click J[12] | 29 years/F | No | p-ANCA, c-ANCA, ANA |
Geller L et al.[13] | 50 years/F | Yes, WBC -2,700/μL, ANC -1,400/μL | p-ANCA, IgM ACL |
Han C et al.[14] | 52 years/F | Yes, WBC -2,400/μL, ANC -1,400/μL | p-ANCA, c-ANCA, IgM ACL |
Ching J et al.[15]/ Mouzakis J et al.[16] | 54 years/F | Yes, WBC -3,900/μL, ANC -300/μL | p-ANCA, IgM ACL |
Jacob RS et al.[17] | 41 years/F | Yes, WBC -1,100/μL, ANC -670/μL | p-ANCA, c-ANCA, IgM ACL, ANA, anti-ds-DNA,anti-HNE |
48 years/F | Yes, WBC -800/μL, ANC -300/μL | p-ANCA, c-ANCA, IgM ACL, ANA, anti-ds-DNA,anti-HNE | |
Lung D et al.[18] | 44 years/F | Yes, ANC -270/μL | Not reported |
Zwang NA et al.[19] | 52 years/M | No | p-ANCA, c-ANCA, IgM ACL, ANA, LAC, anti-HNE, anti-ds-DNA, |
Chung C et al.[20] | 46 years/F | No | p-ANCA, c-ANCA, IgM ACL |
46 years/F | Yes, WBC and ANC not specified | p-ANCA, c-ANCA, IgM ACL | |
37 years/M | No | p-ANCA, ANA | |
50 years/M | No | p-ANCA, ANA | |
Jenkins J et al.[21] | 47 years/M | No | p-ANCA |
John S et al.[22] | 52 years/F | Yes, WBC -2,900/μL, ANC -638/μL | p-ANCA +, anti ds-DNA+ |
Arora et al. [current report] | 44 years/F | Yes, WBC -2,600/μL, ANC -900/μL | p-ANCA+, LAC+ |