From: Care for hospitalized patients with unhealthy alcohol use: a narrative review
Initial oral medication dose | Frequency | Medication half-life |
---|---|---|
Diazepam 10 to 20 mg if CIWA-Ar ≥ 8 to 10 | Repeat same dose hourly until | Long half-life may provide smoother withdrawal, but may accumulate in elderly or those with liver disease. |
CIWA-Ar < 10 | ||
Chlordiazepoxide 50 mg if CIWA-Ar > 9 | Repeat 50 mg hourly until CIWA-Ar < 10 | Intermediate half-life may provide smoother withdrawal than lorazepam. |
Lorazepam 2 to 4 mg if CIWA-Ar ≥ 8 to 10 | Repeat same dose hourly until | Short half-life may increase withdrawal symptoms between doses. May be better tolerated in elderly and liver disease patients. |
 | CIWA-Ar < 10 |  |