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Table 1 Search strategy to identify studies, by database

From: Systematic review of the pharmacological treatment of alcohol use disorders in individuals infected with hepatitis C

Database Search terms Number of hits Number of included articles
MEDLINE (Search terms via Pubmed)* (“Hepatitis C” OR HCV) AND (“alcohol dependence” OR alcoholism OR “alcohol-dependent”) AND (pharmacological treatment OR drug therapy OR disulfiram OR naltrexone OR acamprosate OR baclofen OR ondansetron OR topiramate) 138 3
Embase (MeSH terms via Ovid) #1: Hepatitis C OR Hepatitis C virus 92110 3 (duplicates)
#2: Alcoholism [subheading: drug therapy] 5267
#3: Disulfiram 7571
#4: Naltrexone 11449
#5: Acamprosate 1772
#6: Baclofen 14259
#7: Topiramate 14850
#8: Ondansetron 12818
#9: #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 60923
#10: #1 AND #9 237
#11: Limit #10 to human studies and year 1993 to December 2013 (final result) 225
PsycINFO (MeSH terms via Ovid) #1: Hepatitis 1821 2 (duplicates)
#2: Alcoholism 24628
#3: #1 AND #2 62
#4: Limit #3 to human studies and year 1993 to December 2013 54
Cochrane Central Register of Controlled Trials (MeSH terms via Ovid) #1: Alcoholism 2130 0
#2: Hepatitis C 707
#3: #1 AND #2 4
#4: Limit #3 to year 1993 to December 2013 4
Clinicaltrials.gov (unpublished) “Hepatitis C” AND “alcohol” 149 1 (underway; no results yet)
  1. *limits: human studies and studies between 1993 and December 2013.
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