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Table 6 Optimal and most accurate AUDIT-C thresholds

From: Validation of the AUDIT-C in adults seeking help with their drinking online

Drinking category

Selected thresholds by sex, evaluations with and without optimism

Sensitivity (%) (95% CI)

Specificity (%) (95% CI)

LR+c (95% CI)

LR−d (95% CI)

Sensitivity + specificity

% Correctly classified (95% CI)

Above weekly limitsa

Optimal

Female ≥8

With optimism

69.78 (67.64, 71.85)

81.92 (75.45, 87.29)

3.86 (3.58, 4.16)

0.37 (0.27, 0.51)

151.7

70.82 (68.80, 72.78)

Optimism-adjusted

76.33 (74.34, 78.24)

72.88 (65.70, 79.28)

2.81 (2.56, 3.08)

0.32 (0.25, 0.41)

149.21

76.04 (74.13, 77.87)

Male ≥8

With optimism

82.14 (80.08, 84.08)

66.29 (58.84, 73.19)

2.44 (2.19, 2.72)

0.27 (0.21, 0.34)

148.43

80.42 (78.41, 82.31)

Optimism-adjusted

85.10 (83.16, 86.89)

57.87 (50.25, 65.21)

2.02 (1.78, 2.29)

0.26 (0.21, 0.32)

142.97

82.13 (80.18, 83.96)

Most accurate

Female ≥4

With optimism

99.63 (99.23, 99.85)

16.38 (11.26, 22.68)

1.19 (0.85, 1.66)

0.02 (0.01, 0.04)

116.01

92.45 (91.22, 93.56)

Optimism-adjusted

98.61 (97.98, 99.09)

25.42 (19.19, 32.50)

1.32 (1.03, 1.70)

0.05 (0.03, 0.07)

124.03

92.30 (91.07, 93.42)

Male ≥5

With optimism

99.18 (98.56, 99.57)

25.28 (19.08, 32.33)

1.33 (1.03, 1.71)

0.03 (0.02, 0.05)

124.46

91.13 (89.64, 92.46)

Optimism-adjusted

99.18 (98.56, 99.57)

25.28 (19.08, 32.33)

1.33 (1.03, 1.71)

0.03 (0.02, 0.05)

124.46

91.13 (89.64, 92.46)

Higher risk drinkingb

Optimal

Female ≥8

With optimism

81.90 (79.67, 83.97)

61.90 (58.39, 65.33)

2.15 (2.02, 2.28)

0.29 (0.25, 0.34)

143.80

74.33 (72.38, 76.21)

Optimism-adjusted

81.90 (79.67, 83.97)

61.90 (58.39, 65.33)

2.15 (2.02, 2.28)

0.29 (0.25, 0.34)

143.80

74.33 (72.38, 76.21)

Male ≥9

With optimism

76.71 (73.84, 79.41)

65.03 (61.41, 68.53)

2.19 (2.05, 2.34)

0.36 (0.31, 0.42)

141.74

71.60 (69.35, 73.78)

Optimism-adjusted

76.71 (73.84, 79.41)

65.03 (61.41, 68.53)

2.19 (2.05, 2.34)

0.36 (0.31, 0.42)

141.74

71.60 (69.35, 73.78)

Most accurate

Female ≥8

With optimism

81.90 (79.67, 83.97)

61.90 (58.39, 65.33)

2.15 (2.02, 2.28)

0.29 (0.25, 0.34)

143.80

74.33 (72.38, 76.21)

Optimism-adjusted

81.90 (79.67, 83.97)

61.90 (58.39, 65.33)

2.15 (2.02, 2.28)

0.29 (0.25, 0.34)

143.80

74.33 (72.38, 76.21)

Male ≥9

With optimism

76.71 (73.84, 79.41)

65.03 (61.41, 68.53)

2.19 (2.05, 2.34)

0.36 (0.31, 0.42)

141.74

71.60 (69.35, 73.78)

Optimism-adjusted

76.71 (73.84, 79.41)

65.03 (61.41, 68.53)

2.19 (2.05, 2.34)

0.36 (0.31, 0.42)

141.74

71.60 (69.35, 73.78)

  1. aAbove weekly limits >14 units of alcohol in past week (women); >21 units of alcohol in past week (men)
  2. bHigher risk drinking >35 units of alcohol in past week (women); >50 units of alcohol in past week (men)
  3. cLR+ positive likelihood ratio
  4. dLR− negative likelihood ratio