The association between age of onset of opioid use and comorbidity among opioid dependent patients receiving methadone maintenance therapy

Table 2 Multivariable logistic regression analysis: the presence of physical or psychiatric comorbidity (N = 627)

	Odds ratio, (95% confidence interval)	p value
Covariates
Current age (years)	1.05 (1.02, 1.08)	<0.01*
Sex	1.70 (1.04, 2.75)	0.03
BMI	1.02 (0.99, 1.06)	0.19
Methadone dose (mg/day)	1.00 (1.00, 1.01)	0.77
Smoking status	1.56 (0.85, 2.88)	0.15
Age of onset of opioid use categories (in reference to 31 years and older)
17 years old and younger	2.94 (1.20, 7.19)	0.02
18–25 years	1.71 (0.83, 3.51)	0.14
26–30 years	2.05 (0.89, 4.74)	0.09

56 eligible participants were excluded from the multi-variable regression analysis for having missing values for one or more of the covariates of interest. As such, 167, 97, 244 and 119 patients from the 31 years and older, 26–30 years, 18–25 years, and 17 years and younger subgroups were included in the analysis, respectively
* <0.01 = 0.002

ISSN: 1940-0640