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Table 1 Post-release opioid-related overdose mortality: areas of further research

From: A conceptual model for understanding post-release opioid-related overdose risk

Topic

Area of inquiry

Investigation of mechanisms

Chronic pain

Prevalence and self-medication hypothesis

HIV

Rate of post-release opioid-related overdose and living with HIV

Trauma

Rate of post-release opioid-related overdose and trauma exposure

Race

Race and opioid use disorder treatment and OAT access

Suicidality

Rate of post-release opioid-related overdose and suicidality

Mental health (depression, anxiety, and PTSDb)

Prevalence pre and post-release

Non-opioid substance use

Prevalence pre and post-release

 

Intermediate determinants associated with substance use disorders

Disrupted social networks

Interventions to assist re-integration during the post release period

Poverty

Post-release poverty and mental health and substance use

Polydrug use

Prevalence and independent effect of CJa exposure on the risk of polysubstance use

Polypharmacy

Relationship between pre and post-release prescribing of sedating medications

Effect of probation or parole

Independent effect of probation and parole on post-release opioid related overdose mortality

Type of criminal charge or conviction

Relation to stigma and post-release opioid-related overdose risk

Relationships between risk factors

Investigation of the mediating or moderating relationships between risk factors

Investigation of novel interventions

Chronic pain

Non-opioid pain management within jail or prison

Race

Reduction of criminal justice exposure among blacks

Interruptions in care

Improve engagement with healthcare services post-release

Solitary use

Safe inject sites to reduces rates of solitary use post-release

Care coordination

Integrate CJ, healthcare, and community organizations

Naltrexone

Effectiveness of reducing opioid-related overdose mortality

New formulations of medications

Efficacy and effectiveness of extended release buprenorphine

Police diversion programs and drug courts

Process evaluation and effectiveness at reducing criminal justice exposure and opioid-related overdose

Implementation and dissemination

Interrupted opioid use disorder treatment and OATc access

OAT programs pre and post-release

Interrupted naloxone access

Naloxone program pre and post-release

  1. aCriminal justice
  2. bPost-traumatic stress disorder
  3. cOpioid agonist therapy