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Table 2 Factors associated with receiving a prescription for alcohol use disorder pharmacotherapy within 2 years of diagnosis in a large urban academic medical center (n = 21,159)

From: Primary care engagement is associated with increased pharmacotherapy prescribing for alcohol use disorder (AUD)

Variable

Probability,  % (95% CI)a

Adjusted difference, percentage pointsb (95% CI)

p value

Age

 18–29

1.29 (0.90, 1.69)

Ref.

 30–44

2.83 (2.37, 3.28)

1.53 (0.94, 2.12)

< 0.001

 45–64

2.38 (2.07, 2.68)

1.08 (0.58, 1.59)

< 0.001

 65+

0.92 (0.57, 1.27)

-0.37 (-0.90, 0.17)

0.181

Sex

 Male

2.01 (1.78, 2.24)

Ref.

 Female

2.35 (2.00, 2.71)

0.34 (− 0.09, 0.77)

0.109

Race/ethnicity

 Non-hispanic white

2.86 (2.29, 3.42)

Ref.

 Hispanic

2.71 (2.10, 3.32)

− 0.15 (− 0.99, 0.69)

0.730

 Non-hispanic black

1.65 (1.37, 1.93)

− 1.20 (− 1.84, − 0.57)

< 0.001

 Any othera or undetermined race

2.07 (1.75, 2.39)

− 0.79 (− 1.44, − 0.14)

0.011

Insurance status

 Public

2.16 (1.92, 2.40)

Ref.

 Private

2.06 (1.72, 2.41)

− 0.09 (− 0.53, 0.34)

0.679

 Self-pay or undetermined

1.89 (0.71, 3.08)

− 0.27 (− 1.48, 0.95)

0.685

Charlson score

 0

2.41 (2.09, 2.72)

Ref.

 1–2

2.41 (2.04, 2.78)

0.00 (-0.50, 0.50)

0.998

 3+

1.16 (0.86, 1.47)

-1.24 (-1.71, -0.78)

< 0.001

Year to cohort entry

 2010

1.60 (1.28, 1.92)

Ref.

 2011

2.06 (1.62, 2.50)

0.46 (− 0.08, 1.01)

0.091

 2012

1.95 (1.53, 2.38)

0.36 (− 0.18, 0.89)

0.188

 2013

2.52 (2.05, 2.99)

0.92 (0.35, 1.49)

0.001

 2014

2.70 (2.20, 3.20)

1.10 (0.50, 1.69)

< 0.001

Psychiatric comorbidity

 No

1.52 (1.32, 1.73)

Ref.

 Yes

3.34 (2.89, 3.78)

1.81 (1.31, 2.31)

< 0.001

Emergency visits

 0 visits

2.16 (1.90, 2.41)

Ref.

 

 1 visits

2.15 (1.92, 2.38)

− 0.01 (− 0.05, 0.03)

0.686

Inpatient admissions

 0 admissions

1.78 (1.58, 1.98)

Ref.

 

 1 admission

1.98 (1.79, 2.16)

0.22 (0.13, 0.30)

< 0.001

Outpatient psychiatry visits

 0 visits

1.96 (1.78, 2.15)

Ref.

 

 5 visits

2.15 (1.95, 2.35)

0.19 (0.14, 0.24)

< 0.001

Outpatient substance use treatment visits

 0 visits

2.07 (1.88, 2.26)

Ref.

 

 5 visits

2.65 (2.32, 2.97)

0.52 (0.31, 0.73)

< 0.001

Level of primary care engagement

 No primary care

1.61 (1.39, 1.84)

Ref.

 

 Limited primary care

2.56 (2.06, 3.06)

0.95 (0.40, 1.50)

< 0.001

 Engaged with primary care

2.89 (2.44, 3.34)

1.28 (0.76, 1.79)

< 0.001

  1. aRefers to the adjusted probability of receiving a prescription for alcohol use disorder pharmacotherapy, obtained from a multivariable logistic regression model adjusting for each factor presented in the table and exposure of interest. See Additional file 1: Appendix 4 for further details
  2. bRefers to the difference in the probability of receiving a prescription for alcohol use disorder pharmacotherapy, after adjusting for all other factors described in the table