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Table 2 Factors associated with receiving a prescription for alcohol use disorder pharmacotherapy within 2 years of diagnosis in a large urban academic medical center (n = 21,159)

From: Primary care engagement is associated with increased pharmacotherapy prescribing for alcohol use disorder (AUD)

Variable Probability,  % (95% CI)a Adjusted difference, percentage pointsb (95% CI) p value
Age
 18–29 1.29 (0.90, 1.69) Ref.
 30–44 2.83 (2.37, 3.28) 1.53 (0.94, 2.12) < 0.001
 45–64 2.38 (2.07, 2.68) 1.08 (0.58, 1.59) < 0.001
 65+ 0.92 (0.57, 1.27) -0.37 (-0.90, 0.17) 0.181
Sex
 Male 2.01 (1.78, 2.24) Ref.
 Female 2.35 (2.00, 2.71) 0.34 (− 0.09, 0.77) 0.109
Race/ethnicity
 Non-hispanic white 2.86 (2.29, 3.42) Ref.
 Hispanic 2.71 (2.10, 3.32) − 0.15 (− 0.99, 0.69) 0.730
 Non-hispanic black 1.65 (1.37, 1.93) − 1.20 (− 1.84, − 0.57) < 0.001
 Any othera or undetermined race 2.07 (1.75, 2.39) − 0.79 (− 1.44, − 0.14) 0.011
Insurance status
 Public 2.16 (1.92, 2.40) Ref.
 Private 2.06 (1.72, 2.41) − 0.09 (− 0.53, 0.34) 0.679
 Self-pay or undetermined 1.89 (0.71, 3.08) − 0.27 (− 1.48, 0.95) 0.685
Charlson score
 0 2.41 (2.09, 2.72) Ref.
 1–2 2.41 (2.04, 2.78) 0.00 (-0.50, 0.50) 0.998
 3+ 1.16 (0.86, 1.47) -1.24 (-1.71, -0.78) < 0.001
Year to cohort entry
 2010 1.60 (1.28, 1.92) Ref.
 2011 2.06 (1.62, 2.50) 0.46 (− 0.08, 1.01) 0.091
 2012 1.95 (1.53, 2.38) 0.36 (− 0.18, 0.89) 0.188
 2013 2.52 (2.05, 2.99) 0.92 (0.35, 1.49) 0.001
 2014 2.70 (2.20, 3.20) 1.10 (0.50, 1.69) < 0.001
Psychiatric comorbidity
 No 1.52 (1.32, 1.73) Ref.
 Yes 3.34 (2.89, 3.78) 1.81 (1.31, 2.31) < 0.001
Emergency visits
 0 visits 2.16 (1.90, 2.41) Ref.  
 1 visits 2.15 (1.92, 2.38) − 0.01 (− 0.05, 0.03) 0.686
Inpatient admissions
 0 admissions 1.78 (1.58, 1.98) Ref.  
 1 admission 1.98 (1.79, 2.16) 0.22 (0.13, 0.30) < 0.001
Outpatient psychiatry visits
 0 visits 1.96 (1.78, 2.15) Ref.  
 5 visits 2.15 (1.95, 2.35) 0.19 (0.14, 0.24) < 0.001
Outpatient substance use treatment visits
 0 visits 2.07 (1.88, 2.26) Ref.  
 5 visits 2.65 (2.32, 2.97) 0.52 (0.31, 0.73) < 0.001
Level of primary care engagement
 No primary care 1.61 (1.39, 1.84) Ref.  
 Limited primary care 2.56 (2.06, 3.06) 0.95 (0.40, 1.50) < 0.001
 Engaged with primary care 2.89 (2.44, 3.34) 1.28 (0.76, 1.79) < 0.001
  1. aRefers to the adjusted probability of receiving a prescription for alcohol use disorder pharmacotherapy, obtained from a multivariable logistic regression model adjusting for each factor presented in the table and exposure of interest. See Additional file 1: Appendix 4 for further details
  2. bRefers to the difference in the probability of receiving a prescription for alcohol use disorder pharmacotherapy, after adjusting for all other factors described in the table