|
Variable
|
Probability, % (95% CI)a
|
Adjusted difference, percentage pointsb (95% CI)
|
p value
|
|---|
|
Age
|
|
18–29
|
1.29 (0.90, 1.69)
|
Ref.
|
–
|
|
30–44
|
2.83 (2.37, 3.28)
|
1.53 (0.94, 2.12)
|
< 0.001
|
|
45–64
|
2.38 (2.07, 2.68)
|
1.08 (0.58, 1.59)
|
< 0.001
|
|
65+
|
0.92 (0.57, 1.27)
|
-0.37 (-0.90, 0.17)
|
0.181
|
|
Sex
|
|
Male
|
2.01 (1.78, 2.24)
|
Ref.
|
–
|
|
Female
|
2.35 (2.00, 2.71)
|
0.34 (− 0.09, 0.77)
|
0.109
|
|
Race/ethnicity
|
|
Non-hispanic white
|
2.86 (2.29, 3.42)
|
Ref.
|
–
|
|
Hispanic
|
2.71 (2.10, 3.32)
|
− 0.15 (− 0.99, 0.69)
|
0.730
|
|
Non-hispanic black
|
1.65 (1.37, 1.93)
|
− 1.20 (− 1.84, − 0.57)
|
< 0.001
|
|
Any othera or undetermined race
|
2.07 (1.75, 2.39)
|
− 0.79 (− 1.44, − 0.14)
|
0.011
|
|
Insurance status
|
|
Public
|
2.16 (1.92, 2.40)
|
Ref.
|
–
|
|
Private
|
2.06 (1.72, 2.41)
|
− 0.09 (− 0.53, 0.34)
|
0.679
|
|
Self-pay or undetermined
|
1.89 (0.71, 3.08)
|
− 0.27 (− 1.48, 0.95)
|
0.685
|
|
Charlson score
|
|
0
|
2.41 (2.09, 2.72)
|
Ref.
|
–
|
|
1–2
|
2.41 (2.04, 2.78)
|
0.00 (-0.50, 0.50)
|
0.998
|
|
3+
|
1.16 (0.86, 1.47)
|
-1.24 (-1.71, -0.78)
|
< 0.001
|
|
Year to cohort entry
|
|
2010
|
1.60 (1.28, 1.92)
|
Ref.
|
–
|
|
2011
|
2.06 (1.62, 2.50)
|
0.46 (− 0.08, 1.01)
|
0.091
|
|
2012
|
1.95 (1.53, 2.38)
|
0.36 (− 0.18, 0.89)
|
0.188
|
|
2013
|
2.52 (2.05, 2.99)
|
0.92 (0.35, 1.49)
|
0.001
|
|
2014
|
2.70 (2.20, 3.20)
|
1.10 (0.50, 1.69)
|
< 0.001
|
|
Psychiatric comorbidity
|
|
No
|
1.52 (1.32, 1.73)
|
Ref.
|
–
|
|
Yes
|
3.34 (2.89, 3.78)
|
1.81 (1.31, 2.31)
|
< 0.001
|
|
Emergency visits
|
|
0 visits
|
2.16 (1.90, 2.41)
|
Ref.
| |
|
1 visits
|
2.15 (1.92, 2.38)
|
− 0.01 (− 0.05, 0.03)
|
0.686
|
|
Inpatient admissions
|
|
0 admissions
|
1.78 (1.58, 1.98)
|
Ref.
| |
|
1 admission
|
1.98 (1.79, 2.16)
|
0.22 (0.13, 0.30)
|
< 0.001
|
|
Outpatient psychiatry visits
|
|
0 visits
|
1.96 (1.78, 2.15)
|
Ref.
| |
|
5 visits
|
2.15 (1.95, 2.35)
|
0.19 (0.14, 0.24)
|
< 0.001
|
|
Outpatient substance use treatment visits
|
|
0 visits
|
2.07 (1.88, 2.26)
|
Ref.
| |
|
5 visits
|
2.65 (2.32, 2.97)
|
0.52 (0.31, 0.73)
|
< 0.001
|
|
Level of primary care engagement
|
|
No primary care
|
1.61 (1.39, 1.84)
|
Ref.
| |
|
Limited primary care
|
2.56 (2.06, 3.06)
|
0.95 (0.40, 1.50)
|
< 0.001
|
|
Engaged with primary care
|
2.89 (2.44, 3.34)
|
1.28 (0.76, 1.79)
|
< 0.001
|
- aRefers to the adjusted probability of receiving a prescription for alcohol use disorder pharmacotherapy, obtained from a multivariable logistic regression model adjusting for each factor presented in the table and exposure of interest. See Additional file 1: Appendix 4 for further details
- bRefers to the difference in the probability of receiving a prescription for alcohol use disorder pharmacotherapy, after adjusting for all other factors described in the table
