Neurocognitive domain | Diagnosis of cannabis use disorder | Diagnosis of cocaine use disorder | Diagnosis of major depressive disorder | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Yes (n = 42) | No (n = 54) |  |  | Yes (n = 57) | No (n = 39) |  |  | Yes (n = 35) | No (n = 61) |  |  |
 | M (SD) | M (SD) | t-test | Cohen’s d | M (SD) | M (SD) | t-test | Cohen’s d | M (SD) | M (SD) | t-test | Cohen’s d |
Global NC functioning | 42.7 (5.7) | 40.7 (6.9) | − 1.5 | 0.31 | 42.1 (6.7) | 40.8 (6.1) | − 1.0 | 0.20 | 39.9 (7.0) | 42.5 (6.0) | 1.9* | 0.41 |
Executive functioning | 45.6 (7.3) | 42.1 (7.9) | − 2.3** | 0.46 | 44.9 (8.1) | 41.7 (6.9) | − 2.0* | 0.42 | 41.6 (8.0) | 44.7 (7.5) | 1.9* | 0.40 |
Learning | 35.3 (9.1) | 33.6 (7.3) | − 1.0 | 0.21 | 33.6 (7.8) | 35.4 (9.0) | 1.0 | 0.22 | 33.2 (7.7) | 35.0 (8.6) | 1.0 | 0.22 |
Memory | 36.4 (8.1) | 34.7 (9.3) | − 0.9 | 0.19 | 35.1 (8.5) | 36.1 (9.3) | 0.5 | 0.11 | 34.7 (8.7) | 35.9 (8.9) | 0.6 | 0.14 |
Attention/working memory | 46.0 (9.9) | 40.8 (8.6) | − 2.8*** | 0.57 | 45.3 (9.6) | 39.8 (8.5) | − 2.9*** | 0.60 | 39.7 (9.2) | 45.0 (9.2) | 2.7*** | 0.58 |
Speed of information processing | 47.9 (7.4) | 48.2 (10.0) | 0.1 | 0.03 | 48.7 (9.3) | 47.1 (8.3) | − 0.9 | 0.18 | 46.0 (9.6) | 49.2 (8.3) | 1.7* | 0.36 |
Motor skills | 42.1 (9.5) | 41.9 (11.0) | − 0.1 | 0.02 | 41.2 (10.5) | 43.2 (10.1) | 0.9 | 0.19 | 38.4 (9.4) | 44.1 (10.3) | 2.6** | 0.57 |
Verbal fluency | 45.7 (9.1) | 43.8 (10.5) | − 1.5 | 0.19 | 46.0 (10.7) | 42.6 (8.3) | − 1.7* | 0.35 | 46.0 (10.9) | 43.9 (9.3) | − 1.0 | 0.21 |