Table 2 CSP#2014, VA–BRAVE study assessments

Biological assessments

 Urine pregnancy test

√

√

√

√

√

 Physical exam

√

Week 24

√

 Liver and kidney function, complete blood count (CBC)

√

Weeks 4, 12, 24

√

 Electrocardiogram (EKG)

√

Week 24*

 Urine toxicology test

√

√

√

√

√

 Blood HIV, hepatitis B (HBV), and hepatitis C (HCV)

√

Week 24

√

 Blood buprenorphine and norbuprenorphine

√

Week 24

√

Interviewer administered assessments

 The MINI International Neuropsychic Interview (MINI) [39]

√

√

√

 Clinical Opiate Withdrawal Scale (COWS) [40]

*

√

*

*

*

*

Clinical Institute Withdrawal Scale (CIWA-Ar) [41]

√

*

*

*

*

*

*

 Patient Health Questionnaire-9 (PHQ-9, item 9 only) [42]

√

√

√

√

√

 Timeline follow-back [43]

√

√

√

√

√

 Concomitant medications

√

√

√

√

 Opioid craving and overdose form

√

√

√

√

 PEG3 (pain, enjoyment, general activity)

√

√

√

√

 Service utilization review form (SURF)

√

√

√

 HIV risk behaviors

√

Weeks 12, 24, 36

√

 Criminal justice involvement

√

Week 24

√

 Alcohol Use Disorders Identification Test (AUDIT) [44]

√

√

 Demographics and military history

√

 Modified substance use and medical history

√

 Columbia Suicide Severity Rating Scale (C-SSRS) [45]

√

 Study Medication Adherence Visual Analog Scale (VAS)

√

√

√

 Serious/adverse event

*

*

*

*

*

*

Self-report assessments

 Veterans Rand-12

√

√

√

 Patient Health Questinnaire-9 (PHQ 9)

√

Weeks 12, 24, 36

√

 Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5)

√

Weeks 12, 24, 36

√

 COVID-19 Questionnaire

√

Weeks 12, 24, 36

√