Table 1 Study assessments

Time (weeks)

0

4

52, 104, 156

Inclusion/Exclusion Criteria

X

Written Informed Consent

X

Patient characteristics

X

Medical History

X

Retention^a

X

X

X

Opioid agonist prescription^a

X

X

X

Treatment adherence^a

X

X

X

Frequency of visits^a

X

X

X

Treatment Outcomes Profile (TOP)^b

X

X

X

Health section of Opiate Treatment Index (OTI)^b, including nose-related problems

X

X

X

Symptom-Checklist 27 (SCL-27)^b

X

X

X

Adverse Events^b

X

X

X

Opioid Agonist Scale^1,c

X

X

VAS Subjective effects^2,c

X

X

VAS Craving^c

X

X

X

VAS Satisfaction^c

X

X

X