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Table 2 Test characteristics of Opioid Classifier across a range of cutpoints in calibrated model

From: External validation of an opioid misuse machine learning classifier in hospitalized adult patients

Cutpoint

Sensitivity (95% CI)

Specificity (95% CI)

PPV (95% CI)

NPV (95% CI)

0.35

0.86 (0.83, 0.89)

0.99 (0.99, 0.99)

0.67 (0.64, 0.71)

0.99 (0.99, 0.99)

0.40

0.83 (0.80, 0.86)

0.99 (0.99, 0.99)

0.69 (0.65, 0.72)

0.99 (0.99, 0.99)

0.42a

0.81 (0.77, 0.84)

0.99 (0.99, 0.99)

0.7 (0.67, 0.74)

0.99 (0.99, 0.99)

0.45

0.79 (0.75, 0.82)

0.99 (0.99, 0.99)

0.71 (0.67, 0.74)

0.99 (0.99, 0.99)

0.50a

0.78 (0.74, 0.81)

0.99 (0.99, 0.99)

0.72 (0.68, 0.75)

0.99 (0.99, 0.99)

0.55

0.64 (0.60, 0.68)

0.99 (0.99, 0.99)

0.77 (0.74, 0.81)

0.99 (0.99, 0.99)

0.60

0.56 (0.52, 0.60)

0.99 (0.99, 0.99)

0.82 (0.78, 0.85)

0.99 (0.99, 0.998)

  1. aYouden’s (J) Statistic; PPV, positive predictive value; NPV,  negative predictive value