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  1. Alcohol is challenging to discuss, and patients may be reluctant to disclose drinking partly because of concern about being judged. This report presents an overview of the development of a medications review i...

    Authors: Jim McCambridge, Karl Atkin, Ranjita Dhital, Brent Foster, Brendan Gough, Mary Madden, Stephanie Morris, Ronan O’Carroll, Margaret Ogden, Anne Van Dongen, Sue White, Cate Whittlesea and Duncan Stewart

    Citation: Addiction Science & Clinical Practice 2021 16:63

    Content type: Methodology

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  2. Opioid-related overdoses and harms have been declared a public health emergency in the United States, highlighting an urgent need to implement evidence-based treatments. Contingency management (CM) is one of t...

    Authors: Sara J. Becker, Cara M. Murphy, Bryan Hartzler, Carla J. Rash, Tim Janssen, Mat Roosa, Lynn M. Madden and Bryan R. Garner

    Citation: Addiction Science & Clinical Practice 2021 16:61

    Content type: Study Protocol

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  3. Methamphetamine/amphetamine use has sharply increased among people with opioid use disorder (OUD). It is therefore important to understand whether and how use of these substances may impact receipt of, and out...

    Authors: Madeline C. Frost, Hannah Lampert, Judith I. Tsui, Matthew D. Iles-Shih and Emily C. Williams

    Citation: Addiction Science & Clinical Practice 2021 16:62

    Content type: Review

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  4. Emergency Departments (EDs) are important arenas for the detection of unhealthy substance use. Screening, Brief Intervention, and Referral to Treatment (SBIRT) for unhealthy alcohol use has been used in some E...

    Authors: Ditte Maria Sivertsen, Ulrik Becker, Ove Andersen and Jeanette Wassar Kirk

    Citation: Addiction Science & Clinical Practice 2021 16:60

    Content type: Research

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  5. Urine drug screening (UDS) is commonly used as part of treatment for opioid use disorder (OUD), including treatment with buprenorphine-naloxone for OUD in a primary care setting. Very little is known about th...

    Authors: Halle G. Sobel, Jill S. Warrington, Samuel Francis-Fath, Abigail M. Crocker and Claudia A. Berger

    Citation: Addiction Science & Clinical Practice 2021 16:59

    Content type: Research

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  6. Stimulant use has increased across the US, with concomitant opioid and methamphetamine use doubling between 2011 and 2017. Shifting patterns of polysubstance use have led to rising psychostimulant-involved dea...

    Authors: Mimi Yen Li, George A. Alba, Julian Mitton and Benjamin Bearnot

    Citation: Addiction Science & Clinical Practice 2021 16:57

    Content type: Research

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  7. Nonmedical use of prescription opioids (defined as taking opioid medications for hedonic effects or in a manner other than prescribed) and the use of heroin have emerged in recent years as major public health ...

    Authors: Elizabeth J. D’Amico, Daniel L. Dickerson, Anthony Rodriguez, Ryan A. Brown, David P. Kennedy, Alina I. Palimaru, Carrie Johnson, Rosanna Smart, David J. Klein, Jennifer Parker, Keisha McDonald, Michael J. Woodward and Ninna Gudgell

    Citation: Addiction Science & Clinical Practice 2021 16:56

    Content type: Study Protocol

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  8. Improving access to medication treatment of opioid use disorder (MOUD) is a national priority, yet common modifiable barriers (e.g., limited provider knowledge, negative beliefs about MOUD) often challenge imp...

    Authors: Eric J. Hawkins, Anissa N. Danner, Carol A. Malte, Brittany E. Blanchard, Emily C. Williams, Hildi J. Hagedorn, Adam J. Gordon, Karen Drexler, Jennifer L. Burden, Jennifer Knoeppel, Aline Lott, George G. Sayre, Amanda M. Midboe and Andrew J. Saxon

    Citation: Addiction Science & Clinical Practice 2021 16:55

    Content type: Research

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  9. Findings have been mixed as to whether brief intervention (BI) is appropriate and effective for individuals with more severe alcohol use problems. Motivation to change drinking has been supported as a mechanis...

    Authors: Lindsay R. Meredith, Erica N. Grodin, Mitchell P. Karno, Amanda K. Montoya, James MacKillop, Aaron C. Lim and Lara A. Ray

    Citation: Addiction Science & Clinical Practice 2021 16:54

    Content type: Research

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  10. Opioid use is one of the most critical public health issues as highly potent opioids contribute to rising rates of accidental opioid-related toxicity deaths. This crisis has affected people from all age groups...

    Authors: Kirsten Marchand, Corinne Tallon, Christina Katan, Jill Fairbank, Oonagh Fogarty, Katrina Marie Pellatt, Roxanne Turuba, Steve Mathias and Skye Barbic

    Citation: Addiction Science & Clinical Practice 2021 16:53

    Content type: Study Protocol

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  11. The advent of direct-acting antivirals (DAAs)—a form of hepatitis C (HCV) treatment associated with shorter treatment course and greater efficacy—offers an unprecedented opportunity to eliminate HCV, but only ...

    Authors: Judith I. Tsui, Michael P. Barry, Elizabeth J. Austin, Elsa W. Sweek, Elyse Tung, Ryan N. Hansen, Michael Ninburg, John D. Scott, Sara N. Glick and Emily C. Williams

    Citation: Addiction Science & Clinical Practice 2021 16:52

    Content type: Research

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  12. The Veterans Health Administration (VHA) is invested in expanding access to medication treatment for opioid use disorder (MOUD) to save lives. Access varies across VHA facilities and, thus, requires implementa...

    Authors: Allison M. Gustavson, Marie E. Kenny, Jennifer P. Wisdom, Hope A. Salameh, Princess E. Ackland, Adam J. Gordon and Hildi J. Hagedorn

    Citation: Addiction Science & Clinical Practice 2021 16:51

    Content type: Research

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  13. The COVID-19 pandemic has created a crisis in access to addiction treatment. Programs with residential components have been particularly impacted as they try to keep infection from spreading in facilities and ...

    Authors: Kimberly A. Johnson, Carolyn Keough, Holly Hills, Wouter Vermeer, Rebecca Lengnick-Hall, Moira McNulty, Mark McGovern and Hendricks Brown

    Citation: Addiction Science & Clinical Practice 2021 16:49

    Content type: Commentary

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  14. Smoking is more prevalent and persistent among lower socio-economic status (SES) compared with higher-SES groups, and contributes greatly to SES-based health inequities. Few interventions exist that effectivel...

    Authors: Eline Meijer, Janneke S. Korst, Kristiene G. Oosting, Eline Heemskerk, Sander Hermsen, Marc C. Willemsen, Bas van den Putte, Niels H. Chavannes and Jamie Brown

    Citation: Addiction Science & Clinical Practice 2021 16:48

    Content type: Research

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  15. Little is known about prevalence and treatment of OUD among youth engaged in primary care (PC). Medications are the recommended treatment of opioid use disorder (OUD) for adolescents and young adults (youth). ...

    Authors: Sarah M. Bagley, Laura Chavez, Jordan M. Braciszewski, Mary Akolsile, Denise M. Boudreau, Gwen Lapham, Cynthia I. Campbell, Gavin Bart, Bobbi Jo H. Yarborough, Jeffrey H. Samet, Andrew J. Saxon, Rebecca C. Rossom, Ingrid A. Binswanger, Mark T. Murphy, Joseph E. Glass and Katharine A. Bradley

    Citation: Addiction Science & Clinical Practice 2021 16:46

    Content type: Research

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  16. Office-Based Opioid Treatment (OBOT) is a delivery model which seeks to make medications for opioid use disorder (MOUD), particularly buprenorphine, widely available in general medical clinics and offices. Des...

    Authors: Dominic Hodgkin, Constance Horgan and Gavin Bart

    Citation: Addiction Science & Clinical Practice 2021 16:45

    Content type: Review

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  17. Support from family and other social network elements can be important in helping patients to cope with practical and emotional consequences of diseases. The aim of the study was to examine perception of famil...

    Authors: Bente Birkeland, Bente Weimand, Torleif Ruud, Darryl Maybery and John-Kåre Vederhus

    Citation: Addiction Science & Clinical Practice 2021 16:44

    Content type: Research

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  18. Compared to smokers with favorable socio-economic position (SEP), those with low SEP are less likely to have a successful smoking cessation attempt. Tailored approaches are therefore needed, and general practi...

    Authors: Mégane Héron, Anne-Laurence Le Faou, Gladys Ibanez, Brigitte Métadieu, Maria Melchior and Fabienne El-Khoury Lesueur

    Citation: Addiction Science & Clinical Practice 2021 16:43

    Content type: Research

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  19. Patients with opioid use disorder (OUD) often have complex health care needs. Methadone is one of the medications for opioid use disorder (MOUD) used in the management of OUDs. Highly restrictive methadone tre...

    Authors: Kerry Marshall, Geoffrey Maina and Jordan Sherstobitoff

    Citation: Addiction Science & Clinical Practice 2021 16:42

    Content type: Research

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  20. There is no longer support for the idea that brief intervention programmes alone can contribute meaningfully to the improvement of population health relating to alcohol. As a result, calls for major innovation...

    Authors: Jim McCambridge

    Citation: Addiction Science & Clinical Practice 2021 16:41

    Content type: Commentary

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    The Correction to this article has been published in Addiction Science & Clinical Practice 2021 16:58

  21. Opioid use disorder (OUD) disproportionately impacts rural and American Indian communities and has quadrupled among pregnant individuals nationwide in the past two decades. Yet, limited data are available abou...

    Authors: A. Taylor Kelley, Marcela C. Smid, Jacob D. Baylis, Elizabeth Charron, Amy E. Binns-Calvey, Shayla Archer, Saul J. Weiner, Lori Jo Begaye and Gerald Cochran

    Citation: Addiction Science & Clinical Practice 2021 16:40

    Content type: Study Protocol

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  22. Because of the shortage of health professionals in Chilean primary care, Health Technicians (HT) are providing Brief Interventions (BI) for risky alcohol consumption. We compared the efficacy of two AUDIT-link...

    Authors: Nicolas A. Barticevic, Fernando Poblete, Soledad M. Zuzulich, Victoria Rodriguez, Diego Quevedo, Brena F. Sena and Laura Bradshaw

    Citation: Addiction Science & Clinical Practice 2021 16:39

    Content type: Research

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  23. Measurement-based care (MBC) is the practice of routinely administering standardized measures to support clinical decision-making and monitor treatment progress. Despite evidence of its effectiveness, MBC is r...

    Authors: Justin S. Tauscher, Eliza B. Cohn, Tascha R. Johnson, Kaylie D. Diteman, Richard K. Ries, David C. Atkins and Kevin A. Hallgren

    Citation: Addiction Science & Clinical Practice 2021 16:38

    Content type: Research

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  24. Most Americans with opioid use disorder (OUD) do not receive indicated medical care. A clinical decision support (CDS) tool for primary care providers (PCPs) could address this treatment gap. Our primary objec...

    Authors: Rebecca C. Rossom, JoAnn M. Sperl-Hillen, Patrick J. O’Connor, A. Lauren Crain, Laurel Nightingale, Anne Pylkas, Kristen V. Huntley and Gavin Bart

    Citation: Addiction Science & Clinical Practice 2021 16:37

    Content type: Research

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  25. Opioid withdrawal symptoms prior to buprenorphine initiation may be intolerable and as a result, alternative strategies have emerged. We aim to systematically review the efficacy and safety of buprenorphine in...

    Authors: K. K. Adams, M. Machnicz and D. M. Sobieraj

    Citation: Addiction Science & Clinical Practice 2021 16:36

    Content type: Review

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  26. Gambling-related harm is an increasing recognised problem internationally. Recent years have seen an explosion in opportunities to gamble, both in person and online. Health and other care settings have the pot...

    Authors: Lindsay Blank, Susan Baxter, Helen Buckley Woods and Elizabeth Goyder

    Citation: Addiction Science & Clinical Practice 2021 16:35

    Content type: Research

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  27. Successfully combating the opioid crisis requires patients who misuse opioids to have access to affirming and effective health care. However, there is a shortage of physicians who are willing to work with thes...

    Authors: Berkeley Franz, Lindsay Y. Dhanani and Daniel L. Brook

    Citation: Addiction Science & Clinical Practice 2021 16:33

    Content type: Research

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  28. Youth are frequently exposed to drugs, and most youth who misuse drugs are reluctant to seek help from services due to the worry of others being judgmental, lacking expertise, exposing their personal informati...

    Authors: William Ho Cheung Li, Wei Xia, Laurie Long Kwan Ho, Ankie Tan Cheung, Queenie Kuai I. Leong and Tingna Liang

    Citation: Addiction Science & Clinical Practice 2021 16:32

    Content type: Study Protocol

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  29. Screening, brief intervention and referral to treatment (SBIRT) programmes have resulted in generally positive outcomes in healthcare settings, particularly for problem alcohol use, yet implementation is hampe...

    Authors: Claire van der Westhuizen, Megan Malan, Tracey Naledi, Marinda Roelofse, Bronwyn Myers, Dan J. Stein, Sa’ad Lahri and Katherine Sorsdahl

    Citation: Addiction Science & Clinical Practice 2021 16:31

    Content type: Research

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  30. Homeless youth experience high rates of substance use disorders, exposures to violence, mental and physical health conditions, and mortality. They have been particularly affected by the opioid crisis. However,...

    Authors: Natasha Slesnick, Laura Chavez, Alicia Bunger, Ruri Famelia, Jodi Ford, Xin Feng, Sarah Higgins, Eugene Holowacz, Soren Jaderlund, Ellison Luthy, Allen Mallory, Jared Martin, Laura Walsh, Tansel Yilmazer and Kelly Kelleher

    Citation: Addiction Science & Clinical Practice 2021 16:30

    Content type: Study Protocol

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  31. High comorbidity exists between mental illness and substance use disorders (SUD). Patients in psychiatry living with problematic alcohol or drug consumption can experience a sense of exclusion, where seeking h...

    Authors: Elisabeth Petersén, Anna Thurang and Anne H. Berman

    Citation: Addiction Science & Clinical Practice 2021 16:29

    Content type: Research

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  32. Over the past two decades, the National Drug Abuse Treatment Clinical Trials Network (CTN), a program of the National Institute on Drug Abuse (NIDA), has expanded from the initial six Nodes to 16 Nodes, as a n...

    Authors: Betty Tai, Ronald Dobbins, Quandra Blackeney, David Liu and Landhing Moran

    Citation: Addiction Science & Clinical Practice 2021 16:28

    Content type: Commentary

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  33. South Africa is marked by high rates of both HIV and alcohol use, and there is a detrimental synergistic relationship between these two epidemics. The Institute of Medicine recommends integrated care for alcoh...

    Authors: Caroline C. Kuo, Goodman Sibeko, Morayo Akande, Shaheema Allie, Nurain Tisaker, Dan J. Stein and Sara J. Becker

    Citation: Addiction Science & Clinical Practice 2021 16:27

    Content type: Study Protocol

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  34. While patient-reported treatment dissatisfaction is considered an important factor in determining the success of substance use disorder treatment, the levels of dissatisfaction with opioid agonist therapies (O...

    Authors: Lindsay Mackay, Thomas Kerr, Nadia Fairbairn, Cameron Grant, M.-J. Milloy and Kanna Hayashi

    Citation: Addiction Science & Clinical Practice 2021 16:26

    Content type: Research

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  35. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Miriam T. H. Harris, Alyssa Peterkin, Paxton Bach, Honora Englander, Emily Lapidus, Theresa Rolley, Melissa B. Weimer and Zoe M. Weinstein

    Citation: Addiction Science & Clinical Practice 2021 16:25

    Content type: Correction

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    The original article was published in Addiction Science & Clinical Practice 2021 16:13

  36. Telemedicine (TM) enabled by digital health technologies to provide medical services has been considered a key solution to increasing health care access in rural communities. With the immediate need for remote...

    Authors: Yih-Ing Hser, Allison J. Ober, Alex R. Dopp, Chunqing Lin, Katie P. Osterhage, Sarah E. Clingan, Larissa J. Mooney, Megan E. Curtis, Lisa A. Marsch, Bethany McLeman, Emily Hichborn, Laurie S. Lester, Laura-Mae Baldwin, Yanping Liu, Petra Jacobs and Andrew J. Saxon

    Citation: Addiction Science & Clinical Practice 2021 16:24

    Content type: Commentary

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  37. Unhealthy alcohol use is a key concern for Aboriginal and Torres Strait Islander (‘Indigenous Australian’) communities. Due to systematic disadvantage and inter-generational trauma, Indigenous Australians may ...

    Authors: James H. Conigrave, Emma L. Bradshaw, Katherine M. Conigrave, Richard M. Ryan, Scott Wilson, Jimmy Perry, Michael F. Doyle and K. S. Kylie Lee

    Citation: Addiction Science & Clinical Practice 2021 16:23

    Content type: Research

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  38. Knowledge of medical conditions and their evidence-based medications varies among individuals. This range of knowledge may affect attitudes and influence medical decision-making of both patients and providers....

    Authors: Caroline Shadowen, Rachel Wheeler and Mishka Terplan

    Citation: Addiction Science & Clinical Practice 2021 16:22

    Content type: Research

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  39. The Clinical Institute Withdrawal Assessment for Alcohol-Revised (CIWA-Ar) is commonly used in hospitals to titrate medications for alcohol withdrawal syndrome (AWS), but may be difficult to apply to intensive...

    Authors: Tessa L. Steel, Shewit P. Giovanni, Sarah C. Katsandres, Shawn M. Cohen, Kevin B. Stephenson, Ben Murray, Hillary Sobeck, Catherine L. Hough, Katharine A. Bradley and Emily C. Williams

    Citation: Addiction Science & Clinical Practice 2021 16:21

    Content type: Letter to the Editor

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  40. Chronic pain and heavy drinking are conditions that commonly co-occur among primary care patients. Despite the availability of behavioral interventions that target these conditions individually, engagement and...

    Authors: Tibor P. Palfai, Maya P. L. Kratzer, Natalia E. Morone and Judith A. Bernstein

    Citation: Addiction Science & Clinical Practice 2021 16:20

    Content type: Research

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  41. Opioid misuse screening in hospitals is resource-intensive and rarely done. Many hospitalized patients are never offered opioid treatment. An automated approach leveraging routinely captured electronic health ...

    Authors: Majid Afshar, Brihat Sharma, Sameer Bhalla, Hale M. Thompson, Dmitriy Dligach, Randy A. Boley, Ekta Kishen, Alan Simmons, Kathryn Perticone and Niranjan S. Karnik

    Citation: Addiction Science & Clinical Practice 2021 16:19

    Content type: Research

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  42. Studies indicate high rates of substance use among youth experiencing homelessness (YEH). Further, the social networks of YEH, although multi-dimensional in composition, are largely comprised of other YEH, sub...

    Authors: Joan S. Tucker, David P. Kennedy, Karen Chan Osilla and Daniela Golinelli

    Citation: Addiction Science & Clinical Practice 2021 16:18

    Content type: Study Protocol

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  43. Randomized trials of complex interventions are increasingly including qualitative components to further understand factors that contribute to their success. In this paper, we explore the experiences of health ...

    Authors: Nadia Minian, Aliya Noormohamed, Mathangee Lingam, Laurie Zawertailo, Bernard Le Foll, Jürgen Rehm, Norman Giesbrecht, Andriy V. Samokhvalov, Dolly Baliunas and Peter Selby

    Citation: Addiction Science & Clinical Practice 2021 16:17

    Content type: Research

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  44. For many reasons, the emergency department (ED) is a critical venue to initiate OUD interventions. The prevailing culture of the ED has been that substance use disorders are non-emergent conditions better addr...

    Authors: Ryan P. McCormack, John Rotrosen, Phoebe Gauthier, Gail D’Onofrio, David A. Fiellin, Lisa A. Marsch, Patricia Novo, David Liu, E. Jennifer Edelman, Sarah Farkas, Abigail G. Matthews, Caroline Mulatya, Dagmar Salazar, Jeremy Wolff, Randolph Knight, William Goodman…

    Citation: Addiction Science & Clinical Practice 2021 16:16

    Content type: Study Protocol

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  45. Opioid use disorder continues to be a significant problem in the United States and worldwide. Three medications—methadone, buprenorphine, and extended-release injectable naltrexone,— are efficacious for treati...

    Authors: Matisyahu Shulman, Roger Weiss, John Rotrosen, Patricia Novo, Elizabeth Costello and Edward V. Nunes

    Citation: Addiction Science & Clinical Practice 2021 16:15

    Content type: Review

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