Articles

Addressing complex pharmacy consultations: methods used to develop a person-centred intervention to highlight alcohol within pharmacist reviews of medications

Alcohol is challenging to discuss, and patients may be reluctant to disclose drinking partly because of concern about being judged. This report presents an overview of the development of a medications review i...

Authors: Jim McCambridge, Karl Atkin, Ranjita Dhital, Brent Foster, Brendan Gough, Mary Madden, Stephanie Morris, Ronan O’Carroll, Margaret Ogden, Anne Van Dongen, Sue White, Cate Whittlesea and Duncan Stewart

Project MIMIC (Maximizing Implementation of Motivational Incentives in Clinics): A cluster-randomized type 3 hybrid effectiveness-implementation trial

Opioid-related overdoses and harms have been declared a public health emergency in the United States, highlighting an urgent need to implement evidence-based treatments. Contingency management (CM) is one of t...

Authors: Sara J. Becker, Cara M. Murphy, Bryan Hartzler, Carla J. Rash, Tim Janssen, Mat Roosa, Lynn M. Madden and Bryan R. Garner

The impact of methamphetamine/amphetamine use on receipt and outcomes of medications for opioid use disorder: a systematic review

Methamphetamine/amphetamine use has sharply increased among people with opioid use disorder (OUD). It is therefore important to understand whether and how use of these substances may impact receipt of, and out...

Authors: Madeline C. Frost, Hannah Lampert, Judith I. Tsui, Matthew D. Iles-Shih and Emily C. Williams

An Ethnographic study of unhealthy alcohol use in a Danish Emergency Department

Emergency Departments (EDs) are important arenas for the detection of unhealthy substance use. Screening, Brief Intervention, and Referral to Treatment (SBIRT) for unhealthy alcohol use has been used in some E...

Authors: Ditte Maria Sivertsen, Ulrik Becker, Ove Andersen and Jeanette Wassar Kirk

A Descriptive analysis of urine drug screen results in patients with opioid use disorder managed in a primary care setting

Urine drug screening (UDS) is commonly used as part of treatment for opioid use disorder (OUD), including treatment with buprenorphine-naloxone for OUD in a primary care setting. Very little is known about th...

Authors: Halle G. Sobel, Jill S. Warrington, Samuel Francis-Fath, Abigail M. Crocker and Claudia A. Berger

Correction to: Reimagining brief interventions for alcohol: towards a paradigm fit for the twenty first century

Authors: Jim McCambridge

Care-engaged individuals with polysubstance use in Northeastern US are undertreated for methamphetamine use disorder: a retrospective cohort study

Stimulant use has increased across the US, with concomitant opioid and methamphetamine use doubling between 2011 and 2017. Shifting patterns of polysubstance use have led to rising psychostimulant-involved dea...

Authors: Mimi Yen Li, George A. Alba, Julian Mitton and Benjamin Bearnot

Integrating traditional practices and social network visualization to prevent substance use: study protocol for a randomized controlled trial among urban Native American emerging adults

Nonmedical use of prescription opioids (defined as taking opioid medications for hedonic effects or in a manner other than prescribed) and the use of heroin have emerged in recent years as major public health ...

Authors: Elizabeth J. D’Amico, Daniel L. Dickerson, Anthony Rodriguez, Ryan A. Brown, David P. Kennedy, Alina I. Palimaru, Carrie Johnson, Rosanna Smart, David J. Klein, Jennifer Parker, Keisha McDonald, Michael J. Woodward and Ninna Gudgell

Clinical leaders and providers’ perspectives on delivering medications for the treatment of opioid use disorder in Veteran Affairs’ facilities

Improving access to medication treatment of opioid use disorder (MOUD) is a national priority, yet common modifiable barriers (e.g., limited provider knowledge, negative beliefs about MOUD) often challenge imp...

Authors: Eric J. Hawkins, Anissa N. Danner, Carol A. Malte, Brittany E. Blanchard, Emily C. Williams, Hildi J. Hagedorn, Adam J. Gordon, Karen Drexler, Jennifer L. Burden, Jennifer Knoeppel, Aline Lott, George G. Sayre, Amanda M. Midboe and Andrew J. Saxon

Preliminary study of alcohol problem severity and response to brief intervention

Findings have been mixed as to whether brief intervention (BI) is appropriate and effective for individuals with more severe alcohol use problems. Motivation to change drinking has been supported as a mechanis...

Authors: Lindsay R. Meredith, Erica N. Grodin, Mitchell P. Karno, Amanda K. Montoya, James MacKillop, Aaron C. Lim and Lara A. Ray

Improving Treatment Together: a protocol for a multi-phase, community-based participatory, and co-design project to improve youth opioid treatment service experiences in British Columbia

Opioid use is one of the most critical public health issues as highly potent opioids contribute to rising rates of accidental opioid-related toxicity deaths. This crisis has affected people from all age groups...

Authors: Kirsten Marchand, Corinne Tallon, Christina Katan, Jill Fairbank, Oonagh Fogarty, Katrina Marie Pellatt, Roxanne Turuba, Steve Mathias and Skye Barbic

‘Treat my whole person, not just my condition’: qualitative explorations of hepatitis C care delivery preferences among people who inject drugs

The advent of direct-acting antivirals (DAAs)—a form of hepatitis C (HCV) treatment associated with shorter treatment course and greater efficacy—offers an unprecedented opportunity to eliminate HCV, but only ...

Authors: Judith I. Tsui, Michael P. Barry, Elizabeth J. Austin, Elsa W. Sweek, Elyse Tung, Ryan N. Hansen, Michael Ninburg, John D. Scott, Sara N. Glick and Emily C. Williams

Fluctuations in barriers to medication treatment for opioid use disorder prescribing over the course of a one-year external facilitation intervention

The Veterans Health Administration (VHA) is invested in expanding access to medication treatment for opioid use disorder (MOUD) to save lives. Access varies across VHA facilities and, thus, requires implementa...

Authors: Allison M. Gustavson, Marie E. Kenny, Jennifer P. Wisdom, Hope A. Salameh, Princess E. Ackland, Adam J. Gordon and Hildi J. Hagedorn

Racial/ethnic equity in substance use treatment research: the way forward

Opioid use and opioid-related overdose continue to rise among racial/ethnic minorities. Social determinants of health negatively impact these communities, possibly resulting in poorer treatment outcomes. Resea...

Authors: Kathleen Burlew, Caravella McCuistian and José Szapocznik

Protecting patients and staff in residential treatment centers during exposure to COVID-19: commentary

The COVID-19 pandemic has created a crisis in access to addiction treatment. Programs with residential components have been particularly impacted as they try to keep infection from spreading in facilities and ...

Authors: Kimberly A. Johnson, Carolyn Keough, Holly Hills, Wouter Vermeer, Rebecca Lengnick-Hall, Moira McNulty, Mark McGovern and Hendricks Brown

“At least someone thinks I’m doing well”: a real-world evaluation of the quit-smoking app StopCoach for lower socio-economic status smokers

Smoking is more prevalent and persistent among lower socio-economic status (SES) compared with higher-SES groups, and contributes greatly to SES-based health inequities. Few interventions exist that effectivel...

Authors: Eline Meijer, Janneke S. Korst, Kristiene G. Oosting, Eline Heemskerk, Sander Hermsen, Marc C. Willemsen, Bas van den Putte, Niels H. Chavannes and Jamie Brown

Effects of morbidity on smoking cessation: a national smoking cessation program

In smokers with chronic diseases, we examined the abstinence rates over 6 months and its affecting factors in the context of the Korea National Health Insurance Service (NHIS) smoking cessation program.

Authors: Young-Gyun Seo, Min-Woo Jo, Yu-Jin Paek and Jaekyung Choi

Receipt of medications for opioid use disorder among youth engaged in primary care: data from 6 health systems

Little is known about prevalence and treatment of OUD among youth engaged in primary care (PC). Medications are the recommended treatment of opioid use disorder (OUD) for adolescents and young adults (youth). ...

Authors: Sarah M. Bagley, Laura Chavez, Jordan M. Braciszewski, Mary Akolsile, Denise M. Boudreau, Gwen Lapham, Cynthia I. Campbell, Gavin Bart, Bobbi Jo H. Yarborough, Jeffrey H. Samet, Andrew J. Saxon, Rebecca C. Rossom, Ingrid A. Binswanger, Mark T. Murphy, Joseph E. Glass and Katharine A. Bradley

Financial sustainability of payment models for office-based opioid treatment in outpatient clinics

Office-Based Opioid Treatment (OBOT) is a delivery model which seeks to make medications for opioid use disorder (MOUD), particularly buprenorphine, widely available in general medical clinics and offices. Des...

Authors: Dominic Hodgkin, Constance Horgan and Gavin Bart

Perceived family cohesion, social support, and quality of life in patients undergoing treatment for substance use disorders compared with patients with mental and physical disorders

Support from family and other social network elements can be important in helping patients to cope with practical and emotional consequences of diseases. The aim of the study was to examine perception of famil...

Authors: Bente Birkeland, Bente Weimand, Torleif Ruud, Darryl Maybery and John-Kåre Vederhus

Smoking cessation using preference-based tools: a mixed method pilot study of a novel intervention among smokers with low socioeconomic position

Compared to smokers with favorable socio-economic position (SEP), those with low SEP are less likely to have a successful smoking cessation attempt. Tailored approaches are therefore needed, and general practi...

Authors: Mégane Héron, Anne-Laurence Le Faou, Gladys Ibanez, Brigitte Métadieu, Maria Melchior and Fabienne El-Khoury Lesueur

Plausibility of patient-centred care in high-intensity methadone treatment: reflections of providers and patients

Patients with opioid use disorder (OUD) often have complex health care needs. Methadone is one of the medications for opioid use disorder (MOUD) used in the management of OUDs. Highly restrictive methadone tre...

Authors: Kerry Marshall, Geoffrey Maina and Jordan Sherstobitoff

Reimagining brief interventions for alcohol: towards a paradigm fit for the twenty first century?

There is no longer support for the idea that brief intervention programmes alone can contribute meaningfully to the improvement of population health relating to alcohol. As a result, calls for major innovation...

Authors: Jim McCambridge

Development of an unannounced standardized patient protocol to evaluate opioid use disorder treatment in pregnancy for American Indian and rural communities

Opioid use disorder (OUD) disproportionately impacts rural and American Indian communities and has quadrupled among pregnant individuals nationwide in the past two decades. Yet, limited data are available abou...

Authors: A. Taylor Kelley, Marcela C. Smid, Jacob D. Baylis, Elizabeth Charron, Amy E. Binns-Calvey, Shayla Archer, Saul J. Weiner, Lori Jo Begaye and Gerald Cochran

A Health Technician-delivered Brief Intervention linked to AUDIT for reduction of alcohol use in Chilean primary care: a randomized controlled trial

Because of the shortage of health professionals in Chilean primary care, Health Technicians (HT) are providing Brief Interventions (BI) for risky alcohol consumption. We compared the efficacy of two AUDIT-link...

Authors: Nicolas A. Barticevic, Fernando Poblete, Soledad M. Zuzulich, Victoria Rodriguez, Diego Quevedo, Brena F. Sena and Laura Bradshaw

What do clinicians want? Understanding frontline addiction treatment clinicians’ preferences and priorities to improve the design of measurement-based care technology

Measurement-based care (MBC) is the practice of routinely administering standardized measures to support clinical decision-making and monitor treatment progress. Despite evidence of its effectiveness, MBC is r...

Authors: Justin S. Tauscher, Eliza B. Cohn, Tascha R. Johnson, Kaylie D. Diteman, Richard K. Ries, David C. Atkins and Kevin A. Hallgren

A pilot study of the functionality and clinician acceptance of a clinical decision support tool to improve primary care of opioid use disorder

Most Americans with opioid use disorder (OUD) do not receive indicated medical care. A clinical decision support (CDS) tool for primary care providers (PCPs) could address this treatment gap. Our primary objec...

Authors: Rebecca C. Rossom, JoAnn M. Sperl-Hillen, Patrick J. O’Connor, A. Lauren Crain, Laurel Nightingale, Anne Pylkas, Kristen V. Huntley and Gavin Bart

Initiating buprenorphine to treat opioid use disorder without prerequisite withdrawal: a systematic review

Opioid withdrawal symptoms prior to buprenorphine initiation may be intolerable and as a result, alternative strategies have emerged. We aim to systematically review the efficacy and safety of buprenorphine in...

Authors: K. K. Adams, M. Machnicz and D. M. Sobieraj

Should screening for risk of gambling-related harm be undertaken in health, care and support settings? A systematic review of the international evidence

Gambling-related harm is an increasing recognised problem internationally. Recent years have seen an explosion in opportunities to gamble, both in person and online. Health and other care settings have the pot...

Authors: Lindsay Blank, Susan Baxter, Helen Buckley Woods and Elizabeth Goyder

Facilitating rapid access to addiction treatment: a randomized controlled trial

Obtaining timely access to addiction medicine treatment for patients with substance use disorders is challenging and patients often have to navigate complex referral pathways. This randomized controlled trial ...

Authors: Anita Srivastava, Sarah Clarke, Kate Hardy and Meldon Kahan

Physician blame and vulnerability: novel predictors of physician willingness to work with patients who misuse opioids

Successfully combating the opioid crisis requires patients who misuse opioids to have access to affirming and effective health care. However, there is a shortage of physicians who are willing to work with thes...

Authors: Berkeley Franz, Lindsay Y. Dhanani and Daniel L. Brook

A medical peer-delivered intervention comprising brief motivational interviewing via instant-messaging interaction to reduce drug misuse among youth in Hong Kong: A protocol for a randomised controlled trial

Youth are frequently exposed to drugs, and most youth who misuse drugs are reluctant to seek help from services due to the worry of others being judgmental, lacking expertise, exposing their personal informati...

Authors: William Ho Cheung Li, Wei Xia, Laurie Long Kwan Ho, Ankie Tan Cheung, Queenie Kuai I. Leong and Tingna Liang

Patient outcomes and experience of a task-shared screening and brief intervention service for problem substance use in South African emergency centres: a mixed methods study

Screening, brief intervention and referral to treatment (SBIRT) programmes have resulted in generally positive outcomes in healthcare settings, particularly for problem alcohol use, yet implementation is hampe...

Authors: Claire van der Westhuizen, Megan Malan, Tracey Naledi, Marinda Roelofse, Bronwyn Myers, Dan J. Stein, Sa’ad Lahri and Katherine Sorsdahl

Housing, opportunities, motivation and engagement (HOME) for homeless youth at-risk for opioid use disorder: study protocol for a randomized controlled trial

Homeless youth experience high rates of substance use disorders, exposures to violence, mental and physical health conditions, and mortality. They have been particularly affected by the opioid crisis. However,...

Authors: Natasha Slesnick, Laura Chavez, Alicia Bunger, Ruri Famelia, Jodi Ford, Xin Feng, Sarah Higgins, Eugene Holowacz, Soren Jaderlund, Ellison Luthy, Allen Mallory, Jared Martin, Laura Walsh, Tansel Yilmazer and Kelly Kelleher

Staff experiences of encountering and treating outpatients with substance use disorder in the psychiatric context: a qualitative study

High comorbidity exists between mental illness and substance use disorders (SUD). Patients in psychiatry living with problematic alcohol or drug consumption can experience a sense of exclusion, where seeking h...

Authors: Elisabeth Petersén, Anna Thurang and Anne H. Berman

The NIDA clinical trials network: evolving, expanding, and addressing the opioid epidemic

Over the past two decades, the National Drug Abuse Treatment Clinical Trials Network (CTN), a program of the National Institute on Drug Abuse (NIDA), has expanded from the initial six Nodes to 16 Nodes, as a n...

Authors: Betty Tai, Ronald Dobbins, Quandra Blackeney, David Liu and Landhing Moran

Advancing a cascading train-the-trainer model of frontline HIV service providers in South Africa: protocol of an implementation trial

South Africa is marked by high rates of both HIV and alcohol use, and there is a detrimental synergistic relationship between these two epidemics. The Institute of Medicine recommends integrated care for alcoh...

Authors: Caroline C. Kuo, Goodman Sibeko, Morayo Akande, Shaheema Allie, Nurain Tisaker, Dan J. Stein and Sara J. Becker

The relationship between opioid agonist therapy satisfaction and fentanyl exposure in a Canadian setting

While patient-reported treatment dissatisfaction is considered an important factor in determining the success of substance use disorder treatment, the levels of dissatisfaction with opioid agonist therapies (O...

Authors: Lindsay Mackay, Thomas Kerr, Nadia Fairbairn, Cameron Grant, M.-J. Milloy and Kanna Hayashi

Correction to: Adapting inpatient addiction medicine consult services during the COVID‑19 pandemic

An amendment to this paper has been published and can be accessed via the original article.

Authors: Miriam T. H. Harris, Alyssa Peterkin, Paxton Bach, Honora Englander, Emily Lapidus, Theresa Rolley, Melissa B. Weimer and Zoe M. Weinstein

Is telemedicine the answer to rural expansion of medication treatment for opioid use disorder? Early experiences in the feasibility study phase of a National Drug Abuse Treatment Clinical Trials Network Trial

Telemedicine (TM) enabled by digital health technologies to provide medical services has been considered a key solution to increasing health care access in rural communities. With the immediate need for remote...

Authors: Yih-Ing Hser, Allison J. Ober, Alex R. Dopp, Chunqing Lin, Katie P. Osterhage, Sarah E. Clingan, Larissa J. Mooney, Megan E. Curtis, Lisa A. Marsch, Bethany McLeman, Emily Hichborn, Laurie S. Lester, Laura-Mae Baldwin, Yanping Liu, Petra Jacobs and Andrew J. Saxon

Alcohol consumption and dependence is linked to the extent that people experience need satisfaction while drinking alcohol in two Aboriginal and Torres Strait Islander communities

Unhealthy alcohol use is a key concern for Aboriginal and Torres Strait Islander (‘Indigenous Australian’) communities. Due to systematic disadvantage and inter-generational trauma, Indigenous Australians may ...

Authors: James H. Conigrave, Emma L. Bradshaw, Katherine M. Conigrave, Richard M. Ryan, Scott Wilson, Jimmy Perry, Michael F. Doyle and K. S. Kylie Lee

Patient and provider knowledge of and attitudes toward medical conditions and medication during pregnancy

Knowledge of medical conditions and their evidence-based medications varies among individuals. This range of knowledge may affect attitudes and influence medical decision-making of both patients and providers....

Authors: Caroline Shadowen, Rachel Wheeler and Mishka Terplan

Should the CIWA-Ar be the standard monitoring strategy for alcohol withdrawal syndrome in the intensive care unit?

The Clinical Institute Withdrawal Assessment for Alcohol-Revised (CIWA-Ar) is commonly used in hospitals to titrate medications for alcohol withdrawal syndrome (AWS), but may be difficult to apply to intensive...

Authors: Tessa L. Steel, Shewit P. Giovanni, Sarah C. Katsandres, Shawn M. Cohen, Kevin B. Stephenson, Ben Murray, Hillary Sobeck, Catherine L. Hough, Katharine A. Bradley and Emily C. Williams

Integrating patient perspectives in the development of a mobile health intervention to address chronic pain and heavy drinking in primary care: a qualitative study of patients in an urban, safety-net hospital setting

Chronic pain and heavy drinking are conditions that commonly co-occur among primary care patients. Despite the availability of behavioral interventions that target these conditions individually, engagement and...

Authors: Tibor P. Palfai, Maya P. L. Kratzer, Natalia E. Morone and Judith A. Bernstein

External validation of an opioid misuse machine learning classifier in hospitalized adult patients

Opioid misuse screening in hospitals is resource-intensive and rarely done. Many hospitalized patients are never offered opioid treatment. An automated approach leveraging routinely captured electronic health ...

Authors: Majid Afshar, Brihat Sharma, Sameer Bhalla, Hale M. Thompson, Dmitriy Dligach, Randy A. Boley, Ekta Kishen, Alan Simmons, Kathryn Perticone and Niranjan S. Karnik

Motivational network intervention to reduce substance use and increase supportive connections among formerly homeless emerging adults transitioning to housing: study protocol for a pilot randomized controlled trial

Studies indicate high rates of substance use among youth experiencing homelessness (YEH). Further, the social networks of YEH, although multi-dimensional in composition, are largely comprised of other YEH, sub...

Authors: Joan S. Tucker, David P. Kennedy, Karen Chan Osilla and Daniela Golinelli

Integrating a brief alcohol intervention with tobacco addiction treatment in primary care: qualitative study of health care practitioner perceptions

Randomized trials of complex interventions are increasingly including qualitative components to further understand factors that contribute to their success. In this paper, we explore the experiences of health ...

Authors: Nadia Minian, Aliya Noormohamed, Mathangee Lingam, Laurie Zawertailo, Bernard Le Foll, Jürgen Rehm, Norman Giesbrecht, Andriy V. Samokhvalov, Dolly Baliunas and Peter Selby

Implementation facilitation to introduce and support emergency department-initiated buprenorphine for opioid use disorder in high need, low resource settings: protocol for multi-site implementation-feasibility study

For many reasons, the emergency department (ED) is a critical venue to initiate OUD interventions. The prevailing culture of the ED has been that substance use disorders are non-emergent conditions better addr...

Authors: Ryan P. McCormack, John Rotrosen, Phoebe Gauthier, Gail D’Onofrio, David A. Fiellin, Lisa A. Marsch, Patricia Novo, David Liu, E. Jennifer Edelman, Sarah Farkas, Abigail G. Matthews, Caroline Mulatya, Dagmar Salazar, Jeremy Wolff, Randolph Knight, William Goodman…

Prior National Drug Abuse Treatment Clinical Trials Network (CTN) opioid use disorder trials as background and rationale for NIDA CTN-0100 “optimizing retention, duration and discontinuation strategies for opioid use disorder pharmacotherapy (RDD)”

Opioid use disorder continues to be a significant problem in the United States and worldwide. Three medications—methadone, buprenorphine, and extended-release injectable naltrexone,— are efficacious for treati...

Authors: Matisyahu Shulman, Roger Weiss, John Rotrosen, Patricia Novo, Elizabeth Costello and Edward V. Nunes

Correction to: Proceedings of the Addiction Health Services Research (AHSR) 2020: Virtual Conference: Part 2

An amendment to this paper has been published and can be accessed via the original article.

Authors: