Table 3 Outcome variables and endpoints
Outcome | Endpoint |
|---|---|
Primary | |
 In-hospital initiation of MOUD | Proportion of patients in each arm who initiate MOUD prior to discharge, defined as use of any FDA-approved pharmacotherapy for OUD, including buprenorphine, naltrexone and methadone |
 Linkage to follow-up OUD care | Proportion of patients in each arm who attend at least one OUD-related care visit within 30 days of hospital discharge |
Secondary | |
 OUD-specific discharge plan | Proportion of patients in each arm with an after-hospital care plan that specifies a date and time for a post-discharge addiction care appointment |
 Any post-discharge MOUD utilization | Proportion of patients in each arm who initiate MOUD or continue MOUD treatment within 30 days following hospital discharge |
 Post-discharge outpatient medical care | Proportion of patients in each arm who complete at least one visit to an outpatient medical provider within 30 days of hospital discharge |
 Past 30-day number of days with any opioid use | Mean (or median, depending on distribution) days of use in the past 30 days after hospital discharge |