Table 1 Characteristics and behaviors of participants in CTN clinical trials compared to people with opioid use disorder (1) identifying need for treatment [National Survey on Drug use and Health (NSDUH)], (2) entering substance use treatment [Treatment Episodes Dataset (TEDS)], and (3) from rural regions of the U.S. [Rural Opioids Initiative (ROI)]
Characteristic/ behavior | CTN trials N = 673 N (%) | NSDUHa N = 661,650 N (%) | SMD | TEDS N = 71,751 N (%) | SMD | ROI N = 1933 N (%) | SMD |
|---|---|---|---|---|---|---|---|
Age | 0.085 | 0.16 | 0.19 | ||||
18–29 | 242 (36.0) | 229,715 (34.7) | 20,430 (28.5) | 593 (31) | |||
30–49 | 333 (49.5) | 314,933 (47.6) | 39,559 (55.1) | 1118 (58.5) | |||
50+ | 98 (14.6) | 117,002 (17.7) | 11,762 (16.4) | 199 (10.4) | |||
Male sex | 465 (69.1) | 361,130 (54.6) | 0.30 | 42,805 (59.7) | 0.2 | 1143 (59.1) | 0.21 |
Race/ethnicity | 0.35 | 0.28 | 0.74 | ||||
Non-Hispanic Black/African-American | 117 (17.4) | 65,584 (9.9) | 9720 (13.5) | 56 (2.9) | |||
Non-Hispanic White | 425 (63.2) | 520,682 (78.7) | 51,373 (71.6) | 1591 (82.3) | |||
Hispanic/Latino | 109 (16.2) | 65,379 (9.9) | 6452 (9) | 77 (4) | |||
Other | 22 (3.3) | 10,004 (1.5) | 4206 (5.9) | 209 (10.8) | |||
Education | 0.26 | 0.36 | 0.35 | ||||
< High school | 171 (25.9) | 108,560 (16.4) | 17,366 (25.3) | 437 (22.6) | |||
High school diploma/GED | 225 (34.1) | 229,536 (34.7) | 34,031 (49.5) | 945 (48.9) | |||
Some college | 220 (32.4) | 256,390 (38.8) | 14,152 (20.6) | 507 (26.3) | |||
Bachelor’s or higher | 43 (6.5) | 67,164 (10.2) | 3187 (4.6) | 42 (2.2) | |||
Employed | 190 (24.6) | 284,520 (43) | 0.40 | 18,563 (22) | 0.06 | 765 (39.6) | 0.32 |
Homeless | 185 (27.5) | N/A | 7532 (11b) | 0.43 | 1015 (53.3b) | 0.55 | |
Depression history | 230 (34.2) | 286,791 (44.0b) | 0.20 | N/A | N/A | ||
Heavy alcohol use | 73 (10.8) | 77,006 (11.6) | 0.025 | 5876 (8.2) | 0.09 | 240 (12.4) | 0.05 |
Heavy benzodiazepine use | 65 (9.7) | 105,825 (16) | 0.19 | 5869 (8.2) | 0.05 | 156 (8.1) | 0.06 |
Injection drug use | 443 (65.5) | 240,535 (36.4) | 0.63 | 38,839 (54.1) | 0.26 | 1851 (95.8) | 0.81 |
Average SMD | 0.27 | 0.21 | 0.36 |