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Table 3 Outcomes at baseline and 52 weeks post inclusion across BSCT and MET

From: Predictors of treatment outcome for individuals with alcohol use disorder with a goal of controlled drinking

 

Baseline

52 weeks

Change between groups from baseline and 52 weeks

P

BSCT

n = 125

MET

n = 125

BSCT

MET

BSCT

MET

Estimate

95%-CI

Estimate

95%-CI

Estimate

95%CI

Estimate

95% CI

Estimate (95% CI)

Estimate (95% CI)

Mean weekly alcohol consumption 30 days

21.97

20.16; 23.79

23.13

21.34;24.92

12.53

10.42;14.65

13.86

11.88–15.84

−9.57 (−12.6;6.99)

−9.23 (−11.66;−6.79)

0.839

Percentage of heavy drinking days (of total 30 days)

33.71

29.72; 37.70

38.99

35.01;42.96

18.96

13.85;24.06

18.41

14.15; 22.68

−15.33 (−21.36 to −9.31)

−20.36 (−25.68 to −15.04)

0.207

Proportion with controlled drinking (< 10.0/ < 10.0)

0.09

0.05; 0.17

0.10

0.05; 0.17

0.57

(0.47; 0.67)

0.44

0.35; 0.52

0.47 (0.36 to 0.57)

0.34 (0.25 to 0.43)

0.048*

AUD criteria DSM-5

5.36

4.99; 5.73

5.14

4.78; 5.51

2.46

1.99; 2.93

2.94

2.49; 3.40

2.47 (1.98 to 2.96)

2.94 (2.47 to 3.41)

0.126

PEth

0.63

0.53; 0.74

0.64

0.54; 0.73

0.48

0.32; 0.63

0.49

0.34; 0.63

−0.17 (−0.34 to 0.01)

−0.15 (−0.31 to 0.01)

0.825

CDT

2.11

1.88; 2.35

2.10

1.86; 2.34

1.99

1.67; 2.31

2.15

1.76; 2.55

−0.12 (−0.47 to 0.23)

0.05 (−0.31 to 0.42)

0.368

AUDIT

18.87

17.86; 19.88

19.13

18.10; 20.16

12.54

10.57; 14.51

13.00

11.04; 14.96

−6.32 (−8.32; −4.32)

−6.13 (−7.96; −4.31)

0.820

SIP

11.71

10.63; 12.80

11.92

10.82; 13.03

6.08

4.81; 7.35

6.51

5.40; 7.62

−5.57 (−6.96; −4.18)

−5.44 (−6.73; −4.14)

0.886

PACS

8.34

7.35; 9.32

8.25

7.28; 9.22

5.69

4.25; 7.12

4.92

3.39; 6.45

−2.76 (−4.32; −1.19)

−3.29 (−4.80: −1.78)

0.606

ICS (FC + PC)

35.56

33.52; 37.59

34.83

32.80; 36.86

24.05

20.48; 27.62

24.40

21.91; 26.89

−11.65 (−15.20 to −8.10)

−10.38 (−12.98 to −7.78)

0.563

MADRS-S

9.05

7.82; 10.27

9.62

8.40; 10.84

8.20

5.59; 10.81

8.49

6.34; 10.64

−0.92 (−3.61 to 1.77)

−1.10 (−3.24 to 1.03)

0.876

GAD7

3.39

2.64; 4.15

3.43

2.69; 4.18

3.78

2.48; 5.08

3.90

2.54; 5.25

0.33 (−0.95 to 1.61)

0.48 (−0.93 to 1.90)

0.863

EQ 5D-3L

5.93

5.76; 6.11

6.01

5.84; 6.19

5.95

5.70; 6.20

5.91

5.67; 6.16

0.01 (−0.26 to 0.28)

−0.10 (−0.36 to 0.17)

0.569

EQ 5D VAS

72.65

70.17; 75.13

72.79

70.33; 75.25

74.46

70; .4178.50

77.43

73.63; 81.22

1.81 (−2.20; 5.82)

4.63 (0.73; 8.54)

0.198

Motivation for change

 Importance

9.23

8.90; 9.56

9.31

8.98; 9.65

7.60

6.92; 8.28

7.97

7.41; 8.53

−1.63 (−2.32; −0.95)

−1.34 (−1.90; −0.78)

0.426

 Competence

7.41

7.06; 7.76

6.97

6.61; 7.32

7.72

7.23; 8.20

7.59

7.19; 7.99

0.29 (−0.25; 0.84)

0.63 (0.20; 1.06)

0.299

 

12 weeks

52 weeks

Change between baseline and 52 weeks

P

BSCT

MET

BSCT

MET

BSCT

MET

CSQ 12 weeks

26.31

25.42; 27.21

24.17

23.17; 25.16

25.27

23.93; 26.60

23.73

22.55; 24.92

25.77 (24.87; 26.67)

23.61 (22.73; 24.49)

 < 0.001***

  1. The outcome of controlled drinking (< 10/ < 10) weekly standard drinks (women/men) was calculated as a dichotomous variable and is displayed in a proportion of individuals who attained this drinking level at 52 weeks
  2. Client Satisfaction measured (Client Satisfaction Questionnaire) at 12 and 52 weeks across BSCT and MET
  3. AUD Alcohol use Disorder, DSM-5 = CDT carbohydrate-deficient transferrin, PEth phosphatidylethanol, GGT gamma-glutamyl transferase, AST aspartate amino transferase, ALT alanine amino transferase, AUDIT Alcohol Use Disorders Identification Test, SIP Short Index of Problems, ICS Impaired Control Scale, PACS Penn Alcohol Craving Scale, MADRS-S Montgomery Asberg Depression Rating Scale-Self Rated, GAD 7 Generalized Anxiety Disorder Assessment, Motivation to change VAS Motivation to change, Visual Analogue Scale, EQ 5D VAS EQ 5D Visual Analogue Scale
  4. *p < 0.05, **p ≤ 0.01, ***p < 0.001
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Addiction Science & Clinical Practice

ISSN: 1940-0640