Articles

HIV treatment cascade among female entertainment and sex workers in Cambodia: impact of amphetamine use and an HIV prevention program

HIV prevalence remains high in Cambodia among female entertainment and sex workers (FESW), and amphetamine-type stimulant (ATS) use significantly increases risk of infection. A successful continuum of care (Co...

Authors: Sokunny Muth, Aynar Len, Jennifer L. Evans, Maly Phou, Sophal Chhit, Yuthea Neak, Song Ngak, Ellen S. Stein, Adam W. Carrico, Lisa Maher and Kimberly Page

Integrated HIV care is associated with improved engagement in treatment in an urban methadone clinic

Persons living with HIV and unhealthy substance use are often less engaged in HIV care, have higher morbidity and mortality and are at increased risk of transmitting HIV to uninfected partners. We developed a ...

Authors: Claire Simeone, Brad Shapiro and Paula J. Lum

Screening, treatment initiation, and referral for substance use disorders

Substance use remains a leading cause of preventable death globally. A model of intervention known as screening, brief intervention, and referral to treatment (SBIRT) was developed decades ago to facilitate ti...

Authors: Steven L. Bernstein and Gail D’Onofrio

Comparison of DSM-IV and DSM-5 criteria for alcohol use disorders in VA primary care patients with frequent heavy drinking enrolled in a trial

Criteria for alcohol use disorders (AUD) in the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) were intended to result in a similar prevalence of AUD as DSM-IV. We evaluated the pre...

Authors: Traci Takahashi, Gwen Lapham, Laura J. Chavez, Amy K. Lee, Emily C. Williams, Julie E. Richards, Diane Greenberg, Anna Rubinsky, Douglas Berger, Eric J. Hawkins, Joseph O. Merrill and Katharine A. Bradley

Enhancing patient navigation to improve intervention session attendance and viral load suppression of persons with HIV and substance use: a secondary post hoc analysis of the Project HOPE study

Interventions are needed to improve viral suppression rates among persons with HIV and substance use. A 3-arm randomized multi-site study (Metsch et al. in JAMA 316:156–70, 2016) was conducted to evaluate the ef...

Authors: Maxine Stitzer, Tim Matheson, Colin Cunningham, James L. Sorensen, Daniel J. Feaster, Lauren Gooden, Alexis S. Hammond, Heather Fitzsimons and Lisa R. Metsch

Associations of criminal justice and substance use treatment involvement with HIV/HCV testing and the HIV treatment cascade among people who use drugs in Oakland, California

People who smoke crack cocaine and people who inject drugs are at-risk for criminal justice involvement as well as HIV and HCV infection. Compared to criminal justice involvement, substance use treatment (SUT)...

Authors: Barrot H. Lambdin, Alex H. Kral, Megan Comfort, Andrea M. Lopez and Jennifer Lorvick

Patient-centered primary care for adults at high risk for AUDs: the Choosing Healthier Drinking Options In primary CarE (CHOICE) trial

Most patients with alcohol use disorders (AUDs) never receive alcohol treatment, and experts have recommended management of AUDs in primary care. The Choosing Healthier Drinking Options In primary CarE (CHOICE...

Authors: Katharine A. Bradley, Evette Joy Ludman, Laura J. Chavez, Jennifer F. Bobb, Susan J. Ruedebusch, Carol E. Achtmeyer, Joseph O. Merrill, Andrew J. Saxon, Ryan M. Caldeiro, Diane M. Greenberg, Amy K. Lee, Julie E. Richards, Rachel M. Thomas, Theresa E. Matson, Emily C. Williams, Eric Hawkins…

Rethinking alcohol interventions in health care: a thematic meeting of the International Network on Brief Interventions for Alcohol & Other Drugs (INEBRIA)

In 2016, the International Network on Brief Interventions for Alcohol & Other Drugs convened a meeting titled “Rethinking alcohol interventions in health care”. The aims of the meeting were to synthesize recen...

Authors: Joseph E. Glass, Sven Andréasson, Katharine A. Bradley, Sara Wallhed Finn, Emily C. Williams, Ann-Sofie Bakshi, Antoni Gual, Nick Heather, Marcela Tiburcio Sainz, Vivek Benegal and Richard Saitz

Seek, test, treat: substance-using women in the HIV treatment cascade in South Africa

Women in South Africa who use alcohol and other drugs face multiple barriers to HIV care. These barriers make it difficult for women to progress through each step in the HIV treatment cascade from diagnosis to...

Authors: Wendee M. Wechsberg, Charles van der Horst, Jacqueline Ndirangu, Irene A. Doherty, Tracy Kline, Felicia A. Browne, Jennifer M. Belus, Robin Nance and William A. Zule

Acceptability of a mobile health intervention to enhance HIV care coordination for patients with substance use disorders

Persons living with HIV and substance use disorders face barriers to sustained engagement in medical care, leading to suboptimal antiretroviral treatment outcomes. Innovative mobile technology tools such as cu...

Authors: Ryan P. Westergaard, Andrew Genz, Kristen Panico, Pamela J. Surkan, Jeanne Keruly, Heidi E. Hutton, Larry W. Chang and Gregory D. Kirk

VA residential substance use disorder treatment program providers’ perceptions of facilitators and barriers to performance on pre-admission processes

In the U.S. Department of Veterans Affairs (VA), residential treatment programs are an important part of the continuum of care for patients with a substance use disorder (SUD). However, a limited number of pro...

Authors: Laura S. Ellerbe, Luisa Manfredi, Shalini Gupta, Tyler E. Phelps, Thomas R. Bowe, Anna D. Rubinsky, Jennifer L. Burden and Alex H. S. Harris

The association between age of onset of opioid use and comorbidity among opioid dependent patients receiving methadone maintenance therapy

Opioid use disorder (OUD) affects approximately 21.9 million people worldwide. This study aims to determine the association between age of onset of opioid use and comorbid disorders, both physical and psychiat...

Authors: Leen Naji, Brittany Burns Dennis, Monica Bawor, Michael Varenbut, Jeff Daiter, Carolyn Plater, Guillaume Pare, David C. Marsh, Andrew Worster, Dipika Desai, James MacKillop, Lehana Thabane and Zainab Samaan

Mobile technology intervention to improve care coordination between HIV and substance use treatment providers: development, training, and evaluation protocol

People living with HIV (PLWH) with a substance use disorder (SUD) tend to receive inadequate medical care in part because of a siloed healthcare system in which HIV and substance use services are delivered sep...

Authors: Kasey Claborn, Sara Becker, Susan Ramsey, Josiah Rich and Peter D. Friedmann

Public sector low threshold office-based buprenorphine treatment: outcomes at year 7

Buprenorphine maintenance for opioid dependence remains of limited availability among underserved populations, despite increases in US opioid misuse and overdose deaths. Low threshold primary care treatment mo...

Authors: Elenore Patterson Bhatraju, Ellie Grossman, Babak Tofighi, Jennifer McNeely, Danae DiRocco, Mara Flannery, Ann Garment, Keith Goldfeld, Marc N. Gourevitch and Joshua D. Lee

A systematic review of health economic models of opioid agonist therapies in maintenance treatment of non-prescription opioid dependence

Opioid dependence is a chronic condition with substantial health, economic and social costs. The study objective was to conduct a systematic review of published health-economic models of opioid agonist therapy...

Authors: Mersha Chetty, James J. Kenworthy, Sue Langham, Andrew Walker and William C. N. Dunlop

Prenatal treatment for opioid dependency: observations from a large inner-city clinic

The objective of this study was to review changes in the prevalence of opioid use disorder in pregnancy, and to describe the prenatal care and neonatal outcomes following the implementation of buprenorphine tr...

Authors: Kelley Saia, Sarah M. Bagley, Elisha M. Wachman, Payal P. Patel, Marisa D. Nadas and Susan B. Brogly

Opioid overdose prevention and naloxone rescue kits: what we know and what we don’t know

The opioid use and overdose crisis is persistent and dynamic. Opioid overdoses were initially driven in the 1990s and 2000s by the increasing availability and misuse of prescription opioids. More recently, opi...

Authors: Todd Kerensky and Alexander Y. Walley

Prevalence and factors associated with use of khat: a survey of patients entering HIV treatment programs in Ethiopia

Khat, a plant native to East Africa, has psychoactive constituents similar to amphetamine. Chronic khat use can lead to psychological dependence with multiple physical and mental health harms, complicating cli...

Authors: Alan R. Lifson, Sale Workneh, Tibebe Shenie, Desalegn Admassu Ayana, Zenebe Melaku, Lemlem Bezabih, Hiwot Tekle Waktola, Behailu Dagne, Rose Hilk, Ken C. Winters and Lucy Slater

Validation of the AUDIT-C in adults seeking help with their drinking online

The abbreviated Alcohol Use Disorder Identification Test for Consumption (AUDIT-C) is rapidly becoming the alcohol screening tool of choice for busy practitioners in clinical settings and by researchers keen t...

Authors: Zarnie Khadjesari, Ian R. White, Jim McCambridge, Louise Marston, Paul Wallace, Christine Godfrey and Elizabeth Murray

Technology-assisted intervention for parents of adolescents in residential substance use treatment: protocol of an open trial and pilot randomized trial

Adolescents in residential substance use disorder (SUD) treatment have poor outcomes post-discharge, with follow-up studies suggesting that most adolescents relapse within 90 days. Parenting practices directly...

Authors: Sara J. Becker, Lynn Hernandez, Anthony Spirito and Selby Conrad

Alcohol use in opioid agonist treatment

Alcohol misuse among individuals receiving agonist treatment for an opioid use disorder is common and is associated with significant morbidity and mortality. At present, though substantial research highlights ...

Authors: Seonaid Nolan, Jan Klimas and Evan Wood

Emerging adults in substance misuse intervention: preintervention characteristics and responses to a motivation-enhancing program

Emerging adulthood is an age of particularly risky behavior. Substance misuse during this phase of life can be the beginning of longer-term problems, making intervention programs particularly important. This ...

Authors: Blair Beadnell, Michele A. Crisafulli, Pamela A. Stafford and Erin A. Casey

Proceedings of the 13th annual conference of INEBRIA

Authors: Rod Watson, James Morris, John Isitt, Pablo Barrio, Lluisa Ortega, Antoni Gual, Kenneth Conner, Tracy Stecker, Stephen Maisto, Sophie Paroz, Caroline Graap, Véronique S Grazioli, Jean-Bernard Daeppen, Susan E Collins, Nicolas Bertholet, Jennifer McNeely…

Multifaceted academic detailing program to increase pharmacotherapy for alcohol use disorder: interrupted time series evaluation of effectiveness

Active consideration of effective medications to treat alcohol use disorder (AUD) is a consensus standard of care, yet knowledge and use of these medications are very low across diverse settings. This study ev...

Authors: Alex H. S. Harris, Thomas Bowe, Hildi Hagedorn, Andrea Nevedal, Andrea K. Finlay, Risha Gidwani, Craig Rosen, Chad Kay and Melissa Christopher

Feasibility of a computer-assisted social network motivational interviewing intervention for substance use and HIV risk behaviors for housing first residents

Social networks play positive and negative roles in the lives of homeless people influencing their alcohol and/or other drug (AOD) and HIV risk behaviors.

Authors: Karen Chan Osilla, David P. Kennedy, Sarah B. Hunter and Ervant Maksabedian

Hazardous drinking among young adults seeking outpatient mental health services

Alcohol use can have a significant negative impact on young adults in mental health treatment. This cross-sectional study examined prevalence and factors associated with hazardous drinking among young adults s...

Authors: Anna E. Ordóñez, Rachel Ranney, Maxine Schwartz, Carol A. Mathews and Derek D. Satre

Drinking to toxicity: college students referred for emergency medical evaluation

In 2009, a university adopted a policy of emergency department transport of students appearing intoxicated on campus. The objective was to describe the change in ED referrals after policy initiation and descr...

Authors: Sigmund J. Kharasch, David R. McBride, Richard Saitz and Ward P. Myers

Linking Infectious and Narcology Care (LINC) in Russia: design, intervention and implementation protocol

Russia and Eastern Europe have one of the fastest growing HIV epidemics in the world. While countries in this region have implemented HIV testing within addiction treatment systems, linkage to HIV care from th...

Authors: Natalia Gnatienko, Steve C. Han, Evgeny Krupitsky, Elena Blokhina, Carly Bridden, Christine E. Chaisson, Debbie M. Cheng, Alexander Y. Walley, Anita Raj and Jeffrey H. Samet

Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review

Sleep abnormalities are associated with acute and chronic use of addictive substances. Although sleep complaints associated with use and abstinence from addictive substances are widely recognized, familiarity ...

Authors: Gustavo A. Angarita, Nazli Emadi, Sarah Hodges and Peter T. Morgan

Examining multi-session brief intervention for substance use in primary care: research methods of a randomized controlled trial

Brief interventions such as Screening, a single session of Brief Intervention, and Referral to Treatment (SBIRT) have shown mixed effectiveness in primary care. However, there are indications that multi-sessio...

Authors: Jaclyn E. Chambers, Adam C. Brooks, Rachel Medvin, David S. Metzger, Jennifer Lauby, Carolyn M. Carpenedo, Kevin E. Favor and Kimberly C. Kirby

Study design to evaluate cognitive behavioral therapy among a diverse sample of adults with a first-time DUI offense

Driving under the influence (DUI) of alcohol is a major public health concern, and many individuals continue to drink and drive even after being convicted of a DUI offense. Latinos, in particular, are dispropo...

Authors: Karen Chan Osilla, Katherine E. Watkins, Magdalena Kulesza, Karen Flórez, Marielena Lara-Greenberg and Jeremy N. V. Miles

Study protocol for a web-based personalized normative feedback alcohol intervention for young adult veterans

Young adult veterans from the wars in Iraq and Afghanistan represent a population at-risk for heavy and problematic alcohol use. Unfortunately, few seek treatment for alcohol concerns and those that do seek c...

Authors: Eric R. Pedersen, Grant N. Marshall and Terry L. Schell

Acknowledgement of manuscript reviewers 2015

Authors: Jeffrey H. Samet

A computer-assisted motivational social network intervention to reduce alcohol, drug and HIV risk behaviors among Housing First residents

Individuals transitioning from homelessness to housing face challenges to reducing alcohol, drug and HIV risk behaviors. To aid in this transition, this study developed and will test a computer-assisted interv...

Authors: David P. Kennedy, Sarah B. Hunter, Karen Chan Osilla, Ervant Maksabedian, Daniela Golinelli and Joan S. Tucker

Management of patients with issues related to opioid safety, efficacy and/or misuse: a case series from an integrated, interdisciplinary clinic

Patients, providers, communities and health systems have struggled to achieve balance between access to opioid treatment for chronic pain and its potential harmful consequences: especially misuse, addiction an...

Authors: William C. Becker, Jessica S. Merlin, Ajay Manhapra and Ellen L. Edens

Finding harmony so the music plays on: pragmatic trial design considerations to promote organizational sustainment of an empirically-supported behavior therapy

Pragmatic trials of empirically-supported behavior therapies may inform clinical and policy decisions concerning therapy sustainment. This retrospective trial design paper describes and discusses pragmatic fea...

Authors: Bryan Hartzler, K. Michelle Peavy, T. Ron Jackson and Molly Carney

Implementation of integrated stepped care for unhealthy alcohol use in HIV clinics

Effective counseling and pharmacotherapy for unhealthy alcohol use are rarely provided in HIV treatment settings to patients. Our goal was to describe factors influencing implementation of a stepped care mode...

Authors: E. Jennifer Edelman, Nathan B. Hansen, Christopher J. Cutter, Cheryl Danton, Lynn E. Fiellin, Patrick G. O’Connor, Emily C. Williams, Stephen A. Maisto, Kendall J. Bryant and David A. Fiellin

Physician versus non-physician delivery of alcohol screening, brief intervention and referral to treatment in adult primary care: the ADVISe cluster randomized controlled implementation trial

Unhealthy alcohol use is a major contributor to the global burden of disease and injury. The US Preventive Services Task Force has recommended alcohol screening and intervention in general medical settings sin...

Authors: Jennifer R. Mertens, Felicia W. Chi, Constance M. Weisner, Derek D. Satre, Thekla B. Ross, Steve Allen, David Pating, Cynthia I. Campbell, Yun Wendy Lu and Stacy A. Sterling

Feasibility of a computer-assisted alcohol screening, brief intervention and referral to treatment program for DWI offenders

Alcohol use patterns that are hazardous for one’s health is prevalent among DWI (driving while intoxicated) offenders and is a key predictor of recidivism. The aim of this program evaluation was to determine t...

Authors: Jillian Mullen, Stacy R. Ryan, Charles W. Mathias and Donald M. Dougherty

Health evaluation and referral assistant: a randomized controlled trial to improve smoking cessation among emergency department patients

Computer technologies hold promise for implementing tobacco screening, brief intervention, and referral to treatment (SBIRT). This study aims to evaluate a computerized tobacco SBIRT system called the Health E...

Authors: Edwin D. Boudreaux, Beau Abar, Brianna Haskins, Brigitte Bauman and Grant Grissom

A qualitative study of treatment-seeking heroin users in contemporary China

Heroin has emerged as the primary drug of concern in China, with as many as three million contemporary users. Once a Chinese citizen has been identified by Chinese law enforcement as a ‘drug addict’, that indi...

Authors: Anna Lembke and Niushen Zhang

Predictive validity of two process-of-care quality measures for residential substance use disorder treatment

In order to monitor and ultimately improve the quality of addiction treatment, professional societies, health care systems, and addiction treatment programs must establish clinical practice standards and then ...

Authors: Alex H. S. Harris, Shalini Gupta, Thomas Bowe, Laura S. Ellerbe, Tyler E. Phelps, Anna D. Rubinsky, John W. Finney, Steven M. Asch, Keith Humphreys and Jodie Trafton

Substance use disorder treatment retention and completion: a prospective study of horse-assisted therapy (HAT) for young adults

Keeping substance use disorder patients actively engaged in treatment is a challenge. Horse-assisted therapy (HAT) is increasingly used as a complementary therapy, with claimed motivational and other benefits ...

Authors: Ann Kern-Godal, Espen Ajo Arnevik, Espen Walderhaug and Edle Ravndal

Impact of hepatitis C status on 20-year mortality of patients with substance use disorders

The magnitude of the effect of hepatitis C viral infection on survival is still not fully understood. The objective of this study was to determine whether the presence of hepatitis C viral antibodies in 1991 w...

Authors: Anthony J. Accurso, Darius A. Rastegar, Sharon R. Ghazarian and Michael I. Fingerhood

Contribution of BDNF and DRD2 genetic polymorphisms to continued opioid use in patients receiving methadone treatment for opioid use disorder: an observational study

The heritability of opioid use disorder has been widely investigated; however, the influence of specific genes on methadone treatment outcomes is not well understood. The association between response to methad...

Authors: Monica Bawor, Brittany B. Dennis, Charlie Tan, Guillaume Pare, Michael Varenbut, Jeff Daiter, Carolyn Plater, Andrew Worster, David C. Marsh, Meir Steiner, Rebecca Anglin, Dipika Desai, Lehana Thabane and Zainab Samaan

Interprofessional approaches to integrating SBIRT into students' clinical experiences

Authors: Heather Gotham, Sarah Knopf-Amelung, Ile Haggins, Jolene Lynn, Pam Young, Ronalda Manney and Kendall Kohnle

The role of change facilitators in the implementation of alcohol SBI with public health nurses

Authors: Sherilyn Faulkner, Diane K King, Rebecca Porter and Bridget Hanson

Financial sustainability of screening, brief intervention, and referral to treatment programs in emergency department settings (part of Economics of SBI symposium)

Authors: Alexander J Cowell and William N Dowd

Alcohol-related risk perception in primary care patients screening positive for unhealthy alcohol consumption

Authors: Gallus Bischof, Anja Bischof, Christian Meyer and Hans-Jueegen Rumpf

Mental health and substance misuse 7 years following an Emergency Department admission for alcohol intoxication

Authors: A Adam, M Faouzi, B Yersin, P Bodenmann, JB Daeppen and N Bertholet