Articles

Adapting inpatient addiction medicine consult services during the COVID-19 pandemic

We describe addiction consult services (ACS) adaptations implemented during the Novel Coronavirus Disease 2019 (COVID-19) pandemic across four different North American sites: St. Paul’s Hospital in Vancouver, ...

Authors: Miriam T. H. Harris, Alyssa Peterkin, Paxton Bach, Honora Englander, Emily Lapidus, Theresa Rolley, Melissa B. Weimer and Zoe M. Weinstein

Creation of an algorithm for clinical decision support for treatment of opioid use disorder with buprenorphine in primary care

The treatment capacity for opioid use disorder (OUD) lags far behind the number of patients in need of treatment. Capacity is limited, in part, by the limited number of physicians who offer office based OUD tr...

Authors: Adriane M. dela Cruz, Robrina Walker, Ronny Pipes, Sidarth Wakhlu and Madhukar H. Trivedi

Comparing rapid micro-induction and standard induction of buprenorphine/naloxone for treatment of opioid use disorder: protocol for an open-label, parallel-group, superiority, randomized controlled trial

Buprenorphine/naloxone (Suboxone) is a current first-line treatment for opioid use disorder (OUD). The standard induction method of buprenorphine/naloxone requires patients to be abstinent from opioids and the...

Authors: James S. H. Wong, Mohammadali Nikoo, Jean N. Westenberg, Janet G. Suen, Jennifer Y. C. Wong, Reinhard M. Krausz, Christian G. Schütz, Marc Vogel, Jesse A. Sidhu, Jessica Moe, Shane Arishenkoff, Donald Griesdale, Nickie Mathew and Pouya Azar

Electronic cigarettes’ withdrawal severity symptoms among users during intermittent fasting: a cross-sectional study

Recently, electronic cigarette (e-cig) usage has increased significantly, making it a potentially effective smoking cessation tool. In Muslim countries, most people who use e-cigarettes fast the month of Ramad...

Authors: Muna M. Barakat, Raja’a A. Al-Qudah, Ibrahim Alfayoumi, Hala Jehad Al-Obaidi, Feras Jassim Jirjees and Iman Basheti

PRimary Care Opioid Use Disorders treatment (PROUD) trial protocol: a pragmatic, cluster-randomized implementation trial in primary care for opioid use disorder treatment

Most people with opioid use disorder (OUD) never receive treatment. Medication treatment of OUD in primary care is recommended as an approach to increase access to care. The PRimary Care Opioid Use Disorders t...

Authors: Cynthia I. Campbell, Andrew J. Saxon, Denise M. Boudreau, Paige D. Wartko, Jennifer F. Bobb, Amy K. Lee, Abigail G. Matthews, Jennifer McCormack, David S. Liu, Megan Addis, Andrea Altschuler, Jeffrey H. Samet, Colleen T. LaBelle, Julia Arnsten, Ryan M. Caldeiro, Douglas T. Borst…

“It’s way more than just writing a prescription”: A qualitative study of preferences for integrated versus non-integrated treatment models among individuals with opioid use disorder

Increasingly, treatment for opioid use disorder (OUD) is offered in integrated treatment models addressing both substance use and other health conditions within the same system. This often includes offering me...

Authors: Elizabeth C. Saunders, Sarah K. Moore, Olivia Walsh, Stephen A. Metcalf, Alan J. Budney, Patricia Cavazos-Rehg, Emily Scherer and Lisa A. Marsch

Information technology and addiction science: promises and challenges

Information technology can be used to advance addiction science and clinical practice.

Authors: Nicolas Bertholet and John A. Cunningham

The impact of project ECHO on physician preparedness to treat opioid use disorder: a systematic review

Opioid use disorder (OUD) is a medical condition that has evolved into a serious and deadly epidemic in the United States. Both medical and psychological interventions are called for to end this growing epidem...

Authors: Hunter M. Puckett, Jenny S. Bossaller and Lincoln R. Sheets

Multiple clinical risks for cannabis users during the COVID-19 pandemic

The pandemic caused by Sars-CoV-2 (COVID-19) has been a great concern for public and mental health systems worldwide. The identification of risk groups is essential for the establishment of preventive and ther...

Authors: Ellen Mello Borgonhi, Vanessa Loss Volpatto, Felipe Ornell, Francisco Diego Rabelo-da-Ponte and Felix Henrique Paim Kessler

Conceptualizing the effects of the COVID-19 pandemic on people with opioid use disorder: an application of the social ecological model

The COVID-19 pandemic has resulted in unparalleled societal disruption with wide ranging effects on individual liberties, the economy, and physical and mental health. While no social strata or population has b...

Authors: Ethan Cowan, Maria R. Khan, Siri Shastry and E. Jennifer Edelman

A novel brief treatment for methamphetamine use disorders in South Africa: a randomised feasibility trial

Effective brief treatments for methamphetamine use disorders (MAUD) are urgently needed to complement longer more intensive treatments in low and middle income countries, including South Africa. To address thi...

Authors: K. Sorsdahl, D. J. Stein, S. Pasche, Y. Jacobs, R. Kader, B. Odlaug, S. Richter, B. Myers and J. E. Grant

A Delphi yarn: applying Indigenous knowledges to enhance the cultural utility of SMART Recovery Australia

Mutual support groups are a popular treatment for substance use and other addictive behaviours. However, little is known about the cultural utility of these programmes for Indigenous peoples.

Authors: Elizabeth Dale, Katherine M. Conigrave, Peter J. Kelly, Rowena Ivers, Kathleen Clapham and K. S. Kylie Lee

Merging statewide data in a public/university collaboration to address opioid use disorder and overdose

Describe methods to compile a unified database from disparate state agency datasets linking person-level data on controlled substance prescribing, overdose, and treatment for opioid use disorder in Connecticut.

Authors: William C. Becker, Robert Heimer, Catherine M. Dormitzer, Molly Doernberg, Gail D’Onofrio, Lauretta E. Grau, Kathryn Hawk, Hsiu-Ju Lin, Alex M. Secora and David A. Fiellin

Proceedings of the Addiction Health Services Research (AHSR) 2020: Virtual Conference: Part 2

Authors:

Proceedings of the Addiction Health Services Research (AHSR) 2020 Virtual Conference: Part 1

Authors: Sara J. Becker

Addressing opioid use disorder among rural pregnant and postpartum women: a study protocol

Opioid use disorder (OUD) among women delivering at a hospital has increased 400% from 1999–2014 in the United States. From the years 2007 to 2016, opioid-related mortality during pregnancy increased over 200%...

Authors: M. Aryana Bryan, Marcela C. Smid, Melissa Cheng, Katherine T. Fortenberry, Amy Kenney, Bhanu Muniyappa, Danielle Pendergrass, Adam J. Gordon and Gerald Cochran

What is the prevalence of current alcohol dependence and how is it measured for Indigenous people in Australia, New Zealand, Canada and the United States of America? A systematic review

Alcohol affects Indigenous communities globally that have been colonised. These effects are physical, psychological, financial and cultural. This systematic review aims to describe the prevalence of current (1...

Authors: Teagan J. Weatherall, Katherine M. Conigrave, James H. Conigrave and K. S. Kylie Lee

What can primary care services do to help First Nations people with unhealthy alcohol use? A systematic review: Australia, New Zealand, USA and Canada

First Nations peoples of Australia, New Zealand, the United States of America (USA) and Canada are more likely to be non-drinkers than other people in these countries. However, those who do drink may be at gre...

Authors: Gemma C. Purcell-Khodr, K. S. Kylie Lee, James H. Conigrave, Emma Webster and Katherine M. Conigrave

Video directly observed therapy intervention using a mobile health application among opioid use disorder patients receiving office-based buprenorphine treatment: protocol for a pilot randomized controlled trial

Office-based buprenorphine treatment of opioid use disorder (OUD) does not typically include in-person directly observed therapy (DOT), potentially leading to non-adherence. Video DOT technologies may safeguar...

Authors: Zachery A. Schramm, Brian G. Leroux, Andrea C. Radick, Alicia S. Ventura, Jared W. Klein, Jeffrey H. Samet, Andrew J. Saxon, Theresa W. Kim and Judith I. Tsui

What constitutes “behavioral health”? Perceptions of substance-related problems and their treatment in primary care

Integrating behavioral health in primary care is a widespread endeavor. Yet rampant variation exists in models and approaches. One significant question is whether frontline providers perceive that behavioral h...

Authors: Ida Q. Chen, Helene Chokron Garneau, Timothy Seay-Morrison, Megan R. Mahoney, Heather Filipowicz and Mark P. McGovern

Integrated stepped alcohol treatment for patients with HIV and at-risk alcohol use: a randomized trial

At-risk levels of alcohol use threaten the health of patients with HIV (PWH), yet evidence-based strategies to decrease alcohol use and improve HIV-related outcomes in this population are lacking. We examined ...

Authors: E. Jennifer Edelman, Stephen A. Maisto, Nathan B. Hansen, Christopher J. Cutter, James Dziura, Yanhong Deng, Lynn E. Fiellin, Patrick G. O’Connor, Roger Bedimo, Cynthia L. Gibert, Vincent C. Marconi, David Rimland, Maria C. Rodriguez-Barradas, Michael S. Simberkoff, Janet P. Tate, Amy C. Justice…

Understanding the client characteristics of Aboriginal residential alcohol and other drug rehabilitation services in New South Wales, Australia

Aboriginal alcohol and other drug residential rehabilitation (residential rehabilitation) services have been providing treatment in Australia of over 50 years. However, there are no studies in Australia or int...

Authors: Douglas B. James, KS Kylie Lee, Tania Patrao, Ryan J. Courtney, Katherine M. Conigrave and Anthony Shakeshaft

Study protocol for a group-based motivational interviewing brief intervention to reduce substance use and sexual risk behavior among young adults experiencing homelessness

Young people experiencing homelessness have alarmingly high rates of alcohol and other drug (AOD) use, which is associated with sexual risk behaviors such as unprotected sex, trading sex, and sex with multiple...

Authors: Joan S. Tucker, Elizabeth J. D’Amico, Eric R. Pedersen, Anthony Rodriguez and Rick Garvey

Study design to evaluate a group-based therapy for support persons of adults on buprenorphine/naloxone

Opioid use disorders (OUDs) have devastating effects on individuals, families, and communities. While medication treatments for OUD save lives and are increasingly utilized, rates of treatment dropout are very...

Authors: Karen Chan Osilla, Kirsten Becker, Liisa Ecola, Brian Hurley, Jennifer K. Manuel, Allison Ober, Susan M. Paddock and Katherine E. Watkins

Assessing the readiness of digital data infrastructure for opioid use disorder research

Gaps in electronic health record (EHR) data collection and the paucity of standardized clinical data elements (CDEs) captured from electronic and digital data sources have impeded research efforts aimed at und...

Authors: Arjun Venkatesh, Caitlin Malicki, Kathryn Hawk, Gail D’Onofrio, Jeremiah Kinsman and Andrew Taylor

Chinese- and English-speaking adult current smokers’ perspectives on smoking and culturally and linguistically appropriate cessation: a qualitative analysis

A lack of culturally and linguistically appropriate smoking cessation intervention programs exist among Chinese-Canadian communities. Smoking cessation programs that are provided in Canadian mainstream culture...

Authors: Iraj Poureslami, Jessica Shum, Niloufar Aran and Noah Tregobov

Choosing internet-based treatment for problematic alcohol use—why, when and how? Users’ experiences of treatment online

Internet-based treatment has emerged as a cost-effective option for reaching people who for different reasons are not reached by traditional treatment. Internet-based treatment for problematic alcohol use, spe...

Authors: Veronica Ekström and Magnus Johansson

Commentary on substance use disorders and risk of suicide in a general US population: a case control study by Lynch et al.

In response to the findings of the Lynch et al. study on the association of suicide mortality and substance use disorder, this commentary addresses the need for increased suicide assessment and screening for p...

Authors: Virna Little and Mary Crawford James

How do state Medicaid programs determine what substance use disorder treatment medications need prior authorization? An overview for clinicians

The process by which state Medicaid programs develop their preferred drug lists, and determine which medications require prior authorization, is opaque to many clinicians. This process is a synthesis of cost a...

Authors: Marcus A. Bachhuber

Problem opioid use and HIV primary care engagement among hospitalized people who use drugs and/or alcohol

There is growing public health concern around the potential impact of the opioid crisis on efforts to eradicate HIV. This secondary analysis seeks to determine if those who report opioids as their primary prob...

Authors: Lacey Critchley, Adam Carrico, Natalie Gukasyan, Petra Jacobs, Raul N. Mandler, Allan E. Rodriguez, Carlos del Rio, Lisa R. Metsch and Daniel J. Feaster

One size doesn’t fit all: a thematic analysis of interviews with people who have stopped participating in Narcotics Anonymous in Norway

For persons with substance use disorders (SUDs), 12-step groups (TSGs) are the most available and used peer-based recovery resource, worldwide. However, disengagement is common, and attrition may partly be due...

Authors: John-Kåre Vederhus, Magnhild Høie and Bente Birkeland

Smartphone apps for managing alcohol consumption: a literature review

Smartphone applications (apps) designed to assist users to reduce hazardous and harmful alcohol consumption show potential as an inexpensive alternative to traditional brief intervention in primary care. The a...

Authors: Stephanie Colbert, Louise Thornton and Robyn Richmond

Development of an integrated digital health intervention to promote engagement in and adherence to medication for opioid use disorder

Buprenorphine-naloxone is an evidence-based treatment for Opioid Use Disorder. However, despite its efficacy, nearly half of participants are unsuccessful in achieving stabilization (i.e., period of time follo...

Authors: Kirsten J. Langdon, Susan Ramsey, Caroline Scherzer, Kate Carey, Megan L. Ranney and Josiah Rich

Health and economic outcomes of treatment with extended-release naltrexone among pre-release prisoners with opioid use disorder (HOPPER): protocol for an evaluation of two randomized effectiveness trials

Persons with an opioid use disorder (OUD) who were incarcerated face many challenges to remaining abstinent; concomitantly, opioid-overdose is the leading cause of death among this population, with the initial...

Authors: Sean M. Murphy, Philip J. Jeng, Sabrina A. Poole, Ali Jalali, Frank J. Vocci, Michael S. Gordon, George E. Woody and Daniel Polsky

Substance use disorders and risk of suicide in a general US population: a case control study

Prior research suggests that substance use disorders (SUDs) are associated with risk of suicide mortality, but most previous work has been conducted among Veterans Health Administration patients. Few studies h...

Authors: Frances L. Lynch, Edward L. Peterson, Christine Y. Lu, Yong Hu, Rebecca C. Rossom, Beth E. Waitzfelder, Ashli A. Owen-Smith, Samuel Hubley, Deepak Prabhakar, L. Keoki Williams, Arne Beck, Gregory E. Simon and Brian K. Ahmedani

Six-month retention and changes in quality of life and substance use from a low-threshold methadone maintenance therapy programme in Durban, South Africa

Emerging data points to a potential heroin use epidemic in South Africa. Despite this, access to methadone maintenance therapy and other evidence-based treatment options remains negligible. We aimed to assess ...

Authors: Andrew Scheibe, Shaun Shelly, Tara Gerardy, Zara von Homeyer, Andrea Schneider, Kalvanya Padayachee, Shalon Balaguru Naidoo, Klaas Mtshweni, Ayanda Matau, Harry Hausler and Monique Marks

A text message intervention for quitting cigarette smoking among young adults experiencing homelessness: study protocol for a pilot randomized controlled trial

Cigarette smoking is much more prevalent among young people experiencing homelessness than in the general population of adolescents and young adults. Although many young homeless smokers are motivated to quit,...

Authors: Joan S. Tucker, Eric R. Pedersen, Sebastian Linnemayr, William G. Shadel, Maria DeYoreo and Rushil Zutshi

Guided web-based treatment program for reducing cannabis use: a randomized controlled trial

The aim of this study was to investigate the effects of a web-based treatment program with therapist guidance for adults and adolescents with regular cannabis use from the general population.

Authors: Kristina Sinadinovic, Magnus Johansson, Ann-Sofie Johansson, Thomas Lundqvist, Philip Lindner and Ulric Hermansson

Introduction to the special issue

This special issue of Addiction Science & Clinical Practice, “Addiction treatment access and utilization among criminal justice involved populations”, presents a series of articles on substance use disorder tr...

Authors: Andrea Finlay, Ingrid Binswanger and Christine Timko

Complementary horse-assisted therapy for substance use disorders: a randomized controlled trial

Treatment completion is the greatest challenge for the treatment of substance use disorders (SUDs). A previous investigation showed that complementary horse-assisted therapy (cHAT) was associated with higher r...

Authors: Francesca Gatti, Espen Walderhaug, Ann Kern-Godal, Jeanette Lysell and Espen Ajo Arnevik

An intervention development for cessation of hookah smoking among Iranian women: study protocol for a systematic and theory-based approach to intervention design

Hookah smoking is an emerging global health issue, especially in Eastern Mediterranean region; and accordingly, women are at the center of this issue as they have a more positive attitude towards hookah smokin...

Authors: Sakineh Dadipoor, Gerjo Kok, Ali Heyrani, Teamur Aghamolaei, Mohtasham Ghaffari and Amin Ghanbarnezhad

Developing a clinical decision support for opioid use disorders: a NIDA center for the clinical trials network working group report

There is an urgent need for strategies to address the US epidemic of prescription opioid, heroin and fentanyl-related overdoses, misuse, addiction, and diversion. Evidence-based treatment such as medications f...

Authors: Gavin B. Bart, Andrew Saxon, David A. Fiellin, Jennifer McNeely, John P. Muench, Christopher W. Shanahan, Kristen Huntley and Robert E. Gore-Langton

Use of urinary naloxone levels in a single provider practice: a case study

Urine drug monitoring for medications for opioid use disorder (MOUD) such as buprenorphine can help to support treatment adherence. The practice of introducing unconsumed medication directly into urine (known ...

Authors: Jill S. Warrington, Kaitlyn Booth, Gregory S. Warrington and Samuel Francis-Fath

Case report: Successful induction of buprenorphine/naloxone using a microdosing schedule and assertive outreach

The requirement for moderate withdrawal prior to initiation can be a barrier to buprenorphine/naloxone induction.

Authors: Jennifer Rozylo, Keren Mitchell, Mohammadali Nikoo, S. Elise Durante, Skye P. Barbic, Daniel Lin, Steve Mathias and Pouya Azar

Design of a randomized controlled trial to Link Infectious and Narcology Care (LINC-II) in St. Petersburg, Russia

If Russia is to achieve the UNAIDS 90-90-90 HIV targets, better approaches to engage, effectively treat, and retain patients in care are needed. This paper describes the protocol of a randomized controlled tri...

Authors: Natalia Gnatienko, Dmitry Lioznov, Anita Raj, Elena Blokhina, Sydney Rosen, Debbie M. Cheng, Karsten Lunze, Sally Bendiks, Ve Truong, Natalia Bushara, Olga Toussova, Emily Quinn, Evgeny Krupitsky and Jeffrey H. Samet

Building a Group-Based Opioid Treatment (GBOT) blueprint: a qualitative study delineating GBOT implementation

Group-Based Opioid Treatment (GBOT) has recently emerged as a mechanism for treating patients with opioid use disorder (OUD) in the outpatient setting. However, the more practical “how to” components of succes...

Authors: Randi Sokol, Mark Albanese, Aaronson Chew, Jessica Early, Ellie Grossman, David Roll, Greg Sawin, Dominic J. Wu and Zev Schuman-Olivier

Outcomes of a novel office-based opioid treatment program in an internal medicine resident continuity practice

The integration of opioid use disorder (OUD) care and competencies in graduate medical education training is needed. Previous research shows improvements in knowledge, attitudes, and practices after exposure t...

Authors: Jarratt D. Pytell, Megan E. Buresh and Ryan Graddy

Longitudinal analysis of HIV-risk behaviors of participants in a randomized trial of prison-initiated buprenorphine

It has been estimated that approximately 15% of people who are incarcerated in the US have histories of opioid use disorder. Relapse to opioid use after release from prison poses a serious risk of HIV infectio...

Authors: Thomas R. Blue, Michael S. Gordon, Robert P. Schwartz, Kathryn Couvillion, Frank J. Vocci, Terrence T. Fitzgerald and Kevin E. O’Grady

Priming primary care providers to engage in evidence-based discussions about cannabis with patients

Cannabis use has become increasingly common in the U.S. in recent years, with legalization for medical and recreational purposes expanding to more states. With this increase in use and access, providers should...

Authors: Devan Kansagara, William C. Becker, Chelsea Ayers and Jeanette M. Tetrault

Sort of a nice distance: a qualitative study of the experiences of therapists working with internet-based treatment of problematic substance use

Internet interventions have been developed and tested for several psychiatric and somatic conditions. Few people with substance use disorders receive treatment and many drug users say that they would prefer ge...

Authors: Veronica Ekström and Magnus Johansson